Chapter 9: Reaction Mechanisms, Pathways, Bioreactions and Bioreactors
Sketch Uncompetitive Inhibition on a Lineweaver-Burk Plot
\( \frac{1}{-r_S} = \frac{1}{V_{\max} (S)} \left( K_M + (S) \left( 1 + \frac{(I)}{K_I} \right) \right) \)
\( = \frac{K_M}{V_{\max}} \left( \frac{1}{(S)} \right) + \frac{1}{V_{\max}} \left( 1 + \frac{(I)}{K_I} \right) \)
Slope remains the same but intercept changes as inhibitor concentration is increased
