Publications � DNA bending
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Ramirez-Carrozzi, V. R. and Kerppola, T. K.� Control
of the orientation of Fos-Jun binding and the transcriptional cooperativity of
Fos-Jun�NFAT1 complexes.� J.
Biol. Chem. 276:21797-21808,� 2001. �[Abstract]
[Full
text] [PDF]
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Ramirez-Carrozzi, VR and Kerppola, TK: Dynamics of
Fos-Jun-NFAT1 complexes.� Proc. Natl.
Acad. Sci. U.S.A. 98:4893-4898, 2001.� [Abstract] [Full
text] [PDF]
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Dlakic M, Grinberg, AV, Leonard, DA and Kerppola, TK:
DNA sequence-dependent folding determines the divergence in binding
specificities between Maf and other bZIP proteins.� EMBO Journal 20: 828‑840, 2001.� [Abstract] [Full text] [PDF]
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Ramirez-Carrozzi, VR and Kerppola, TK: Long-range
electrostatic interactions influence the orientation of Fos-Jun binding at AP-1
sites.� J. Mol. Biol. 305: 411-427,
2001.� [Abstract] [Full
text] [PDF]
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Kerppola, TK:�
Molecular architecture of transcription-regulatory protein complexes.
HHMI Research in Progress, p. 327-328, 2000.�
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text]
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Dlakic, M and Kerppola, TK: DNA structure changes
coupled to protein binding. Encyclopedia of Life Sciences, Macmillan Reference
Ltd., 2000.� [Home page]
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Leonard, DA and Kerppola, TK: DNA bending determines
Fos-Jun heterodimer orientation. Nature Structural Biology, 5:877-881,
1998.� [Abstract] [Full
text] [PDF]
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Kerppola, TK: Transcriptional cooperativity: bending
over backwards and doing the flip. Structure, 6:549-554, 1998.� [Abstract] [Full
text] [PDF]
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Diebold, RJ, Rajaram, N, Leonard, D.A and Kerppola, TK:
Molecular basis of cooperative DNA bending and oriented heterodimer binding in
the NFAT1-Fos-Jun-ARRE2 complex. Proc. Natl. Acad. Sci. U.S.A., 95:7915-7920,
1998.� [Abstract] [Full
text] [PDF]
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Kerppola, TK: Molecular architecture of
transcription factor complexes.� HHMI
Research in Progress, p. 339-340, 1997-1998.�
[Full
text]
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Rajaram, N and Kerppola, TK: DNA bending by Fos-Jun and
the orientation of heterodimer binding depend on sequence of the AP-1 site.
EMBO J, 16:2917-2926, 1997.� [Abstract] [Full Text] [PDF]
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Kerppola, TK and Curran, T: The transcription
activation domains of Fos and Jun induce DNA bending through electrostatic
interactions. EMBO J, 16:2907-2916, 1997.�
[Abstract]
[Full Text] [PDF]
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Leonard, D, Rajaram, N and Kerppola, TK: Structural
basis of DNA bending and oriented heterodimer binding by Fos and Jun. Proc.
Natl. Acad. Sci. U.S.A., 94:4913-4918, 1997. �
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Kerppola, TK: Comparison of DNA bending by Fos-Jun and
phased A tracts by multifactorial phasing analysis.� Biochemistry, 36:10872-10884, 1997.� [Abstract]
[Full
Text] [PDF]
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Kerppola, TK: Molecular architecture of transcription
factor complexes. HHMI Biennial Scientific Report, p. 76-77, 1996-1998.
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Kerppola, TK: Mechanisms of transcriptional
cooperativity.� HHMI Research in
Progress, p. 315-316, 1996. [Full
text]
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Kerppola, TK: Fos and Jun bend the AP-1 site: Effects
of probe geometry on the detection of protein induced DNA bending. Proc. Natl.
Acad. Sci. U.S.A., 93: 10117-10122, 1996.�
[Abstract]
[PDF]
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Kerppola, TK: Mechanisms of transcriptional
cooperativity. HHMI Annual Scientific Report, 86-87, 1995-96.
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Kerppola, TK and Curran, T:� Zen and the art of Fos and Jun.�
Nature, 373: 199-200, 1995.
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Kerppola, TK and Rajaram, N:� Sequence dependence of DNA bending by Fos and Jun.� Biopolymers Gordon Research Conference (C.
Bustamante), Newport, Rhode Island, 1996.
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Kerppola, TK: Fos and Jun bend the AP-1 site: Effects
of probe geometry on the detection of protein induced DNA bending. Proc. Natl.
Acad. Sci. U.S.A., 93: 10117-10122, 1996.�
[Abstract]
[PDF]
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Kerppola, TK: Mechanisms of transcriptional
cooperativity. HHMI Annual Scientific Report, 86-87, 1995-96.
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Kerppola, TK and Curran, T:� Zen and the art of Fos and Jun.�
Nature, 373: 199-200, 1995.
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Kerppola, TK:�
DNA bending specificity among bZIP family proteins.� In Transcription: Mechanisms &
Regulation (ed. R. Conaway and J. Conaway), Raven Press, New York, pp. 387-424,
1994.
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Kerppola, TK:�
DNA bending specificity among bZIP family proteins.� In Transcription: Mechanisms &
Regulation (ed. R. Conaway and J. Conaway), Raven Press, New York, pp. 387-424,
1994.
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Kerppola, TK and Curran, T:� Fos, Jun and GR: Structural and functional interactions.� 75th Annual Meeting of the Endocrine
Society, Las Vegas, Nevada, p. 20, 1993.
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Kerppola, TK, Wang, Y, Griffith, J and Curran, T:� Role of DNA bending in transcription
activation by Fos and Jun family proteins.�
LVIII Cold Spring Harbor Symposium on Quantitative Biology, DNA and
Chromosomes (B. Alberts, B. Stillman), Cold Spring Harbor, New York, p. 90,
1993.
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Kerppola, TK and Curran, T:� Selective DNA bending by a variety of bZIP proteins.� Molecular and Cell Biology, 13 (9):
5479-5489, 1993.� [Abstract]
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Kerppola, TK, Robertson, LM and Curran, T:� DNA bending, protein-protein interactions,
and the regulation of c-fos expression.�
Molecular Basis of Cell Proliferation Gordon Research Conference (T.
Curran and R. Eisenberg), Meriden, New Hampshire, 1993.
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Kerppola, TK and Curran, T:� Selective DNA bending by a variety of bZIP proteins.� Molecular and Cell Biology, 13 (9):
5479-5489, 1993.� [Abstract]
�
Kerppola, TK and Curran, T:� Role of DNA bending in transcription
activation and regulatory specificity among Fos and Jun family proteins.� Journal of Cellular Biochemistry, 17A (6):
79, 1993.
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Kerppola, TK and Curran, T:� DNA bending by Fos and Jun: Structural and functional implications.� In Nucleic Acids and Molecular Biology� Vol. 7 (ed. F. Eckstein and D. Lilley),
Springer-Verlag, London, pp. 70-105, 1993.
� Kerppola, TK and Curran, T:� DNA bending by Fos and Jun:� The flexible hinge model.� Science, 254: 1210-1214, 1991.
� Kerppola, TK and Curran, T:� Fos�Jun heterodimers and Jun homodimers bend DNA in opposite orientations:� Implications for transcription factor cooperativity. Cell, 66: 317-326, 1991.� [Abstract]�
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Kerppola, TK and Kane, CM:� Analysis of the signals for transcription termination by purified
RNA polymerase II.� Biochemistry 29:
269-278, 1990.� [Abstract]
� Kerppola, TK and Kane, CM:� Intrinsic sites of transcription termination and pausing in the c-myc gene.� Molecular and Cell Biology, 8 (10): 4389-4394, 1988.