Michael J. Welsh

Welsh photo

CURRICULUM VITAE

Business Address:

Department of Cell and Developmental Biology
The University of Michigan Medical School
5736 Medical Science II Building 0616
Ann Arbor, Michigan 48109-0616
email: welsh@umich.edu
(734) 763-2549 (office telephone); (734) 763-1166 (FAX)

Citizenship:

United States of America

Education:

B.Sc. (Zoology), Texas A & M University, College Station, Texas (1970)
Graduate School, Texas A & M University, College Station, Texas (1970-72)
Ph.D. (Zoology), University of Western Ontario, London, Ontario, Canada (1977)

Graduate and Postdoctoral Training:

N.R.S.A., NIH Postdoctoral Fellowship, Baylor College of Medicine, July 1977 - June 1979
Postdoctoral Fellowship, Baylor College of Medicine, May 1976 - June 1977
N.S.F. Graduate Fellowship, Texas A & M and University of Western Ontario, 1971 - 1974
N.D.E.A. Graduate Fellowship, Texas A & M University, January 1971 - August 1971

Academic Appointments/Professional Background:

Current Titles:

Professor of Cell & Developmental Biology , University of Michigan, 1990-present
Research Scientist, Reproductive Sciences Program , University of Michigan, 1994-present

Past Appointments:

Interim Chair, Department of Cell & Developmental Biology 9/1/99-8/31/00
Acting Chair, Department of Cell & Developmental Biology 9/1/99-8/31/00
Professor of Anesthesiology, University of Michigan, 1990-1998.
Associate Professor, Anatomy & Cell Biology, University of Michigan, 1985-1990
Associate Research Scientist, Reproductive Sciences Program, University of Michigan, 1985-1994; Director, Laboratory Animal Core Facility, 1984-present
Associate Professor, Anesthesiology, University of Michigan, 1988-1990
Adjunct Associate Professor, Physiology, Southern Illinois University, 1987-89
Assistant Professor, Anatomy & Cell Biology, University of Michigan, 1979-1985
Instructor, Department of Cell Biology, Baylor College of Medicine, 1979
Post-doctoral Fellow, Department of Cell Biology, Baylor College of Medicine, 1976-79
Laboratory Instructor for Undergraduate Botany, Texas A&M University, 1970-1971
Research Assistant, Texas A & M University, 1968-1970

Past and Current Affiliations:

Member, Comprehensive Cancer Center , University of Michigan, 1987-present; Director, Cancer Center Morphology Core Facility, 1987-present
Member, Diabetes Research and Training Center , 1985-present; Member of Operating Committee, 1992-present
Faculty, Toxicology Training Program , University of Michigan, 1991-present
Faculty, Cellular Biotechnology Training Program , University of Michigan, 1992-present
Faculty, Reproductive Sciences Training Program , University of Michigan, 1983-present
Faculty, Cell & Molecular Biology Training Program , University of Michigan, 1981-present
Faculty, Developmental Biology Training Program, University of Michigan, 1984-1994
Faculty, Medical Scientist Training Program , University of Michigan, 1982-present
Faculty, Cellular and Molecular Approaches to Systems and Integrative Biology Training Program , University of Michigan, 1995-present
Faculty, Training Program in Organogenesis , University of Michigan, 1996-present
Visiting Scientist, Department of Reproductive Toxicology (sabbatical), SmithKline Beecham, King of Prussia, PA.  1998-1999

Current Grant Support:

NIH, P01 ES11188, “Metal toxicant effects on small heat-shock protein function”, (MJ Welsh, PI), 8/1/01-7/31/06.  Total direct costs $3,170,935, first year direct costs $575,911.  Total project DC & IC, $4,722,043.

NIH, R01 ES11196,  “Protein responses in cadmium toxicity of renal epithelia”, (E. Shelden, P.I., M.J. Welsh, collaborator).  7/18/01-6/30/05.  Total direct costs $600,000, first year  direct costs $150,000.

NIH, P30 CA46592, "University of Michigan Cancer Center", M. Wicha, P.I., (M.J. Welsh-Director of Morphology Core).  8/01-7/06. Total direct costs $16,858,007,  current year direct costs $3,280,947; total direct costs to Morphology Core $228,079, current year direct costs $42,960.

NIH, R01 DK55602, "Hsp27 in podocyte structure and stress response in nephritic syndrome", (W. Smoyer, M.D., PI, M.J. Welsh co-investigator), 12/99-11/03. Total direct support requested $895,323, first year support requested $171,182.

NIH, F31 HL68424, “Oxidant damage to the heart: The role of hsp27 and hic-5” (M.J. Welsh, PI, Shannon Yancy, fellowship recipient).  Project period 12/01-11/04, total project  award $82,200.

Previous Grant Support:

University of Michigan Biomedical Research Council Equipment Grant, "Zeiss META Detector", 2002, $75,700, M.J. Welsh, PI.

NIH, RO1 ES06265, "Mechanisms of Toxicity in Testes", M.J. Welsh, P.I., 8/96-7/00, total direct support $819,841.

NIH, "Shared Confocal Microscope" (B. Carlson, PI, M Welsh one of several co-investigators) Total Direct costs $365,000

NIH, RO1 ES07006, "Induction of Hsp27 in Abnormal Development", M.J. Welsh, P.I., 6/96-5/99, Total direct support $473,530.

NIH, P30 HD18258, "Center for the Study of Reproduction", A.R. Midgley, P.I., (M.J. Welsh-Director of Laboratory Animal Core Facility) 4/94-3/99. Total direct support $2,583,224.

NIH, RO1 ES06265, "Mechanisms of Toxicity in Testes", M.J. Welsh, PI, 8/93-7/96, total direct support $520,521.

March of Dimes, "The Cellular Stress Response and Toxic Damage", M.J. Welsh, P.I., 2/93-1/95, total direct support $70,910.

NIH, RO1, "Volatile Anesthetic Action and Ca2+ Homeostasis" P. Knight, P.I., M.J. Welsh co-investigator, 4/91-3/96, total direct support $589,000.

NIH, S10 RR05833, "Laser Scanning Confocal Microscope with Image Processing", R. Altschuler, PI, M.J. Welsh, co-investigator. 6/90-5/91, total direct support $267,000.

NIH, RO1 HD17121 "Biochemical Mechanisms in Sertoli-Germ Cell Interactions", M.J. Welsh, PI, 7/88-3/92, total direct support $360,000.

NIH, RO1 DA05066, "Chronic Stimulants and Calmodulin" M. Gnegy, (Pharmacology) P.I., M.J. Welsh, co-PI, 3/89-2/92, total direct support $300,000.

NIH, "Quantitative Image-Intensified Light Microscope System", 1984, Total Support $139,000. (P.R. Knight (Anesthesiology) P.I.; M.J. Welsh, Co-Investigator).

NIH, "Testicular Cell Interactions and Meiosis In Vitro," M. J. Welsh, P.I., 3/82-2/85, Total Direct Support $141,633.

Office of the Associate Dean for Research, University of Michigan Medical School: "Image Processing and Analysis System", 1984-85, $365,000. (MJ Welsh, TG Connelly, and LL Brinkley, co-investigators).

General Motors Corp. "In Vitro System for Testing of Reproductive Toxicity" M.J. Brabec and M.J. Welsh, Co-PI's. 1/85-12/85, $42,100.

NIH, NICHD RO1 HD17121 "Biochemical Mechanism of Sertoli-Germ Cell Interaction," Michael J. Welsh, 1/83 - 9/86, Total Direct Support $136,380.

General Motors Corporation, "In Vitro System for Testing of Reproductive Toxicity", M.J. Brabec and M.J. Welsh, Co-PI's, 1/86-12/86, $46,900.

NIH, NIEHS RO1 ES03451 "Effect of Reproductive Toxicants on Testicular Cells" M.J. Brabec, P.I., M.J. Welsh, Co-Investigator, 9/84-8/87, Total Direct Support $155,000.

NIH, S10 RRO 3380, "No Flow" Cytometer, D.W. Thomas, PI, M.J. Welsh, one of 4 co-investigators on Shared Instrumentation Grant for a Meridian Instrument ACAS 470 Laser Microscope. 12/86-11/87, total direct support $212,900.

NIH, S10 RRO 3431, "Image Analysis System for Two-Dimensional Gels", F.C. Neidhardt, PI, M.J. Welsh, one of 5 co-investigators on shared Instrumentation Grant. 12/86-11/87, total direct support, $146,410.

NIH, NIGMS GM33980, "Calmodulin and Calcium in Mitosis", M.J. Welsh, PI, 10/85-9/88, total direct support, $184,794.

University of Michigan Cancer Research Institute, "Interaction of Rat Testis Sertoli Cells and Germ Cells In Vitro", 1980-81, $4,500, M.J. Welsh, PI.

Rackham Graduate School Faculty Research Grant, "Interaction of Rat Testis Sertoli Cells and Germ Cells In Vitro", 1980-81, $10,000, M.J. Welsh, PI.

Biomedical Research Council Research Grant, "Interaction of Rat Testis Sertoli Cells and Germ Cells In Vitro", 1980-81, $9,154, M.J. Welsh, PI.

Biomedical Research Council Equipment Grant, "Multi-user Liquid Scintillation Counter", 1980, $24,900, M.J. Welsh, PI, with 4 co-investigators.

University of Michigan Cancer Research Institute, "Calmodulin and Gap Junctions", 1981-82, $4,550, M.J. Welsh, PI.

University of Michigan Memorial Phoenix Project, "Activation of Sertoli Cell Adenylate Cyclase by Germ Cells In Vitro", 1982, $4,000, M.J. Welsh, PI.

University of Michigan Cancer Research Institute, "Calmodulin and Calcium in Mitosis", 1983-84, $5,000, M.J. Welsh, PI.

Biomedical Research Council Research Grant, "Calmodulin and Calcium in Mitosis", 1983-84, $3,750, M.J. Welsh, PI.

Office of the Vice President for Research, "Calmodulin and Calcium in Mitosis", 1983-84, $3,750, M.J. Welsh, PI.

Office of the Associate Dean for Research, University of Michigan Medical School, "Low Light Level Video Camera", 1983-84, $9,000, M.J. Welsh, PI.

Biomedical Research Council Equipment Grant, "Gamma Counter", 1985, $8,400, S. Brown, PI, M.J. Welsh, co-investigator.

Biomedical Research Council Equipment Grant, "ACAS 470 No-Flow Cytometer", 1986-87, $25,000, K. Barald, PI, M.J. Welsh, co-investigator.

Training Programs/Grants:

NIH Reproductive Sciences Training Program, 1980-present
NIH Developmental Biology Training Program, 1986-1994
NIH Medical Scientists Training Program, 1980-present
NIH Cell and Molecular Biology Training Program, 1980-present
NIH Toxicology Training Program, 1991-present
NIH Biotechnology Training Program, 1992-present
NIH Systems and Integrative Biology Predoctoral Training Program, 1995-present
NIH Training Program in Organogenesis, 1996-present

Current Teaching:

Dental Histology, 1980, 1985-present, Course Director 1990-1995
Special Projects in Cell and Developmental Biology (student research), 1981-present

Past Teaching:

Botany Laboratory Instructor, 1971
Endocrinology Laboratory Instructor, 1974-76
Medical Histology, 1980-1984
Developmental & Molecular Aspects of Development, 1987-1989
Post Doctoral (M.D.) Research Training Program, 1986-1990
Cellular Biotechnology, 1993, 1994
Medical and Biological Illustration, Histology and Cell Biology Consultant, 1981-1999
Mammalian Reproductive Biology, 1987, 1988, 1990-92, 1994, 1996
Cell Biology, 1979-91, 1994-1998; Course Director, 1985

Administrative Service

Departmental:

Research Committee, 1979-80
Graduate Curriculum and Examination Committee, 1979-80
Faculty Recruitment Committee for two positions, 1980
Social Committee, 1980-82
Cell Biology Laboratories Committee (the central departmental laboratories), 1980-82, 1984-1988; Chairman, 1985
Qualifying Examination Committee 1981, 1983
Chairman, Graduate Admissions Committee, 1982-83
Chairman, ad hoc committee for proposal to BMRC for funds to purchase liquid scintillation counter, 1980
Chairman, ad hoc committee to acquire image analysis system, 1983-1984
Chairman, ad hoc committee to acquire gamma counter from Physiology Department, 1983
Departmental Space Committee, 1983-84
Executive Committee, 1984-94, 1996-99
Appointments and Promotions Committee, 1987-90, 1994-95; Chairman, 1990, 1995
Faculty Search Committees, 1988-89, Two positions 1994-95
Baker Memorial Lecture Committee, 1988-89, 1995-1998
Long Range Planning Committee, 1990-present
Graduate Education Committee, 1993-1995, 1996-1998
Internal Review Committee Member, Entrepreneurial Activities Subcommittee-Chair, 1995-1996.
Associate Chair 1994-present
Acting Chair 1999-2000
Interim Chair 2000-2002
Curriculum Committee, Chair 2002-present

Medical School:

Biomedical Research Council, 1981-82, 1985-1987, Chairman, 1986-87
Research Proposal Reviewer, Biomedical Research Council 1980-83
Jody Ungerleider Memorial Award Committee, 1985-1987, Chairman, 1986
Department of Pathology External Review Committee, 1987-88
Basic Science Research Executive Committee, Cancer Center, 1986-1998, 1999-present
Diabetes Research Center Operating Committee, 1992-present
Basic Science Incentive Salary Task Group, 1993
Operating Committee, Systems & Integrative Biology Predoc. Training Program, 1996-present
Medical School Research Space Advisory Committee member, 1996-1998, 1999-present
Diversity and Career Development Committee member, 1996-present
Faculty Omsbud, 1996-present
Basic Science Chairs Committee,  1999-2002
Dean’s Advisory Council Member, 1999-2002
Research Policy Review Committee, 2001-2002
Biological Sciences Scholars Selection Committee, 2001-2002
Center for the Advancement of Clinical Research Advisory Committee, 2002-present
Diversity Leadership Training Program Stakeholder Group, 2002

University:

Oral Preliminary Examination Committee, Cell and Molecular Biology Program, 1981, 1984, 1985, 1988.
Chairman, Oral Preliminary Examination Committee, Cell and Molecular Biology Program, 1983, 1997
Cell and Molecular Biology Program Executive Committee, 1984
President's Initiatives Program, proposal reviewer, 1987-89
Developmental and Reproductive Biology Executive Committee, 1986-1990
Reproductive Sciences Program Executive Committee 1991-1992
NIH P30 Center for the Study of Reproduction Executive Committee, 1985-89, 1991-94; P30 Center for the Study of Reproduction Steering Committee 1993-present
Core Facility for Aged Rodents, Steering Committee, 1988-present
Cell & Molecular Biology Program Admissions Committee, 1990-1991, 1993-95 Committee Chairman 1994-95
Rackham Graduate School, Divisional Board, Biological Sciences, 1991-1993
Local Arrangements Committee for Society for the Study of Reproduction 1994 meeting in Ann Arbor; Chairman, Reception Planning Subcommittee, 1993-1994
Rackham Graduate School, Dissertation/Thesis Grant Review Committee, 1993-94
Faculty Search Committee for 2 positions in Toxicology, School of Public Health, 1995
Panel member for faculty grievance review board, 1995-1998, 1999-present;  Chair of grievance review board, 11/2001.

City and State:

Co-treasurer, Logan Elementary School PTSO, 1992-93
Member, Michigan Technology Council 1985-87

National:

NIH external reviewer of grant proposals, 1981-82, 1996
NIH ad hoc Study Section member, 1983, 1993, 1996
Reviewer for NSF grants, 1988, 1989
NIH site visit teams:
    University of Illinois Cancer Center, 1988
    McArdle Laboratory (U Wisconsin) Program Project, 1992
    University of California, Davis, Program Project, 1992
    Quadrennial review of the Endocrinology and Reproduction Research Branch of NICHD, 1995
    Washington State University, P01 Program Project, October, 2001
    University of Wisconsin, P30 Center for Developmental and Molecular Toxicology, May 2002
Reviewer for USDA grants, 1989, 1992
National Institute for Environmental Health Sciences Consultant, 1991-present
Publications Committee, Society for the Study of Reproduction, 1990-91
Society of Toxicology, Nominating Committee for Reproductive and Developmental Toxicology Specialty Section 1995-96
Manuscript Reviewer: Biology of Reproduction, Proceedings of the National Academy of Sciences USA, Journal of Reproduction and Fertility, Endocrinology, CRC Press, Journal of Cell Biology, Journal of Biological Chemistry, Journal of Cerebral Blood Flow and Metabolism, Experimental Cell Research, Science, Journal of Histochemistry and Cytochemistry, Cell Motility and Cytoskeleton, Journal of Andrology, Journal of Clinical Investigation, Molecular Endocrinology, Life Sciences-Pharmacology Letters Section, Proceedings of the Society for Experimental Biology and Medicine, Cell Biology International, Molecular and Chemical Neuropathology, Toxicology and Applied Pharmacology, and American Journal of Physiology, and Biochimica et Biophysica Acta

International:

Editor-in-Chief,  Cell Biology and Toxicology, 2002-present

Professional Societies:

American Society for Cell Biology
Society for Developmental Biology
Society for the Study of Reproduction
American Association of Anatomists
Society of Toxicology
American Association for the Advancement of Science

Doctoral Committees:

William G. Frederick, Ph.D. (Anatomy) 1981
Gretchen E. K. Dixon, Ph.D. (Anatomy & Cell Biology) 1982
Patricia Beattie, Ph.D. (Toxicology) 1984
Alison Adams, Ph.D. (Biol. Sciences) 1984
Andrew Abler, Ph.D. (Cell & Molecular Biology Program) 1985
June Kim, Ph.D. (Environmental & Industrial Health) 1985
Glenn J. Triesman, M.D., Ph.D. (Pharmacology) 1985
P. Bagavandos, Ph.D. (Reproductive Endocrinology Program) 1986
George Miller, Ph.D., (Toxicology) 1986
Layla Batarseh, Ph.D., (Toxicology) 1986
Markos Georgiou, Ph.D., (Biological Chemistry) 1986
Kimberley Treinen, Ph.D. (Toxicology) 1986
Jon Aster, M.D., Ph.D. (Human Genetics) 1987
Sumol Pavittranon, Ph.D., (Toxicology) 1988
Jeff Harrison, Ph.D. (Pharmacology) 1988
Robert Zidell, Ph.D. (Environmental & Industrial Health) 1988
Steve Clough, Ph.D. (Toxicology) 1988
Emery Bresnick, Ph.D. (Pharmacology) 1989
Shawn Newton, Ph.D. (Physiology, Southern Illinois Univ. Medical School) 1989
Susan Ford, Ph.D. (Biology) 1989
Usamah Kayyali Ph.D. (Environmental & Industrial Health) 1991
George Wilmont, Ph.D. (Neurosciences) 1991
Lori Mangels, Ph.D. (Pharmacology) 1991
Steve Olsen, M.D., Ph.D. (Neurosciences) 1991
Larry Scherrer, M.D., Ph.D. (Pharmacology) 1992
Guim Kwon, Ph.D. (Pharmacology) 1992
Riva Marcus, Ph.D. (Biology) 1992
Jane Weisen, Ph.D. (Reproductive Sciences, Physiology) 1992
Yiping Yang, Ph.D. (Human Genetics) 1993
Andrea Stout, Ph.D. (Biophysics) 1993
Douglas Sweet, Ph.D. (Biological Chemistry/Biology) 1993
Anna Mitchell, M.D., Ph.D. (Human Genetics) 1994
Ariane McKennan, Ph.D. (Biophysics) 1995
Michael Czar, Ph.D. (Pharmacology) 1995
Mark Qian, Ph.D. (Chemistry) 1996
Eunyong Lee, Ph.D. (Toxicology) 1996
Jeff Pitt, Ph.D. (Toxicology) 1997
Adam Goldsmith, Ph.D. (Pharmacology) 1997
Kim McGinnis (Pharmacology)
Kefei Zheng, Ph.D. (Chemistry) 1998
Sharon Michelhaugh, Ph.D. (Pharmacology) 1998
Paul Kosnick, Ph.D. (Bioengineering) 2000
Eric E Dirnbach, Ph.D. (Biophysics) 2000
Jennifer Magun, M.Sc. (Toxicology) 2001
Kimon Kanelakis, Ph.D. (Pharmacology) 2002

Pre-Doctoral Trainees:

Kenneth Pote, Ph.D. (Anatomy & Cell Biology) 1987, currently owns and operates a bicycle shop in Maine.

Jaime Perry (Anatomy & Cell Biology), transferred to Kent State University, 1987; received Ph.D. in 1992, currently post-doctoral fellow at Mayo Clinic, Rochester, MN.

Stuart Sweet, M.D., Ph.D. (Medical Scientist Training Program and Cell & Molecular Biology Program; winner of MSTP Research Award), 1989; currently Instructor in Pediatrics, Washington University Medical School, St. Louis, MO.

S. Timothy Redmond, Ph.D. (Cell & Molecular Biology Program), 1990; current position unknown.

Gary Pittenger, Ph.D. (Anatomy & Cell Biology), 1990; now Assistant Professor of Internal Medicine and of Anatomy, Eastern Virginia Medical School, Norfolk, VA.

Kok-Wah Hew, Ph.D. (Anatomy & Cell Biology), 1993; currently Project Director, Wyeth.

Jill Pritts, M.Sc. (Physiology), 1997; recipient of U of M Research Partnerships Fellowship and Reproductive Sciences Training Program Fellowship. Currently works for Parke-Davis, Ann Arbor, MI.

Jeff Ballew, M.Sc. (Cell and Molecular Biology) 1999. Currently Research Associate at Mayo Clinic, Rochester, MN.

Chenghua Liu, Ph.D. (Anatomy & Cell Biology), 1999; recipient of University of Michigan Regents Fellowship. Currently a scientist at Hyseq, California.

Yifeng Jia, Ph.D.(Cell & Molecular Biology), 2001 current currently post-doctoral fellow University of Michigan Comprehensive Cancer Center.

Cheryl DeGuzman, M.Sc. (Toxicology), current doctoral candidate student.

Shannon Yancy (Toxicology), current doctoral candidate student.

William Feliciano (Cell and Molecular Biology Training Program), current pre-doctoral student.

Post-Doctoral Trainees and Visiting Scholars:

Mark Ireland, Ph.D., Post-Doctoral trainee 6/83-12/85; now tenured Associate Professor of Anatomy & Cell Biology at Wayne State University Medical School, Detroit, MI 48201

Kimberley Treinen, Ph.D., Post-doctoral Fellow in Developmental Biology, 5/86-6/87, currently Investigator, SmithKline Beecham, King of Prussia, PA.

Ester Goudsmit, Ph.D., Associate Professor of Biology, Oakland University, Rochester, MI 48063, Visiting Scholar 6/86-8/86.

Robert Gilmont, Ph.D., Postdoctoral Fellow in Reproductive Sciences, 6/89-3/93. Currently Research Investigator, Department of Surgery, University of Michigan Medical School.

Stuart Sweet, M.D., Ph.D., Post-doctoral Research Associate, 12/89-6/90. Currently Research Fellow in Pediatrics, Washington University Medical School, St. Louis, MO.

Brian Athey, Ph.D., Postdoctoral Fellow in Developmental Biology, 5/90-6/91, currently Assistant Professor in Cell & Developmental Biology, University of Michigan.

William Wu, Ph.D., Postdoctoral Research Associate, 1/94-4/95, Research Investigator 5/95-6/96, current Research Scientist, Esperion Corp., Ann Arbor, MI

Rainer Benndorf, Ph.D., Visiting Scientist from the Max Delbruck Institute, Berlin, Germany. 1/97-1998, Research Investigator in Cell & Developmental Biology, 1998-2002, currently Assistant Research Scientist, Cell and Developmental Biology.

Yong T. Hou, Ph.D., Research Investigator 1998-2000.  Currently scientist in biotech industry and on Faculty of Shanghai Institute of Materia Medica, Shanghai, PRC.    

Xiankui Sun, Ph.D., Research Associate II, 11/99-present.

Honors and Awards:

N.S.F. Graduate Fellowship, Texas A & M University & Univ. of Western Ontario, 1971-74
N.D.E.A. Graduate Fellowship, Texas A & M University, 1971
Special University Scholarships, University of Western Ontario, 1975, 1976
Detweiler Award, University of Western Ontario, 1977
Postdoctoral Fellowship, Baylor College of Medicine, 1976-1977
N.R.S.A., NIH Postdoctoral Fellowship, Baylor College of Medicine, 1977-1979

Publications:

  1. Welsh MJ, Hanselka CW: 1972. Toxicity and sublethal effects of methyl parathion on the behavior of Siamese fighting fish (Betta splendens). Texas J. Sci. 23: 519-529.
  2. Welsh MJ, Wiebe JP: 1975. Rat Sertoli cells: A rapid method for obtaining viable cells. Endocrinology 96: 618-624
  3. Welsh MJ, Wiebe JP: 1976. Sertoli cells from immature rats: In vitro stimulation of steroid metabolism by FSH. Biochem. Biophys. Res. Commun. 69: 936-941
  4. Welsh, MJ 1977. The capacity of rat Sertoli cells in vitro to metabolize C19 steroids and the age related variation and FSH effect on steroidogenic enzyme activities. Dissertation, University of Western Ontario.
  5. Welsh MJ, Wiebe JP: 1978. Sertoli cell capacity to metabolize C19 steroids: Variation with age and the effect of follicle stimulating hormone. Endocrinology 103: 838-844.
  6. Welsh MJ, Dedman JR, Brinkley BR, Means AR: 1978. Calcium-dependent regulator protein: Localization in the mitotic apparatus of eukaryotic cells. Proc. Natl. Acad. Sci. USA 74: 1867-1871.
  7. Dedman JR, Welsh MJ, Means AR: 1978. Ca2+-dependent regulator: Production and characterization of monospecific antibody. J. Biol. Chem. 253: 7515-7521.
  8. Means AR, Dedman JR, Tindall DJ, Welsh MJ: 1978. Hormonal regulation of Sertoli cells. Int. J. Androl. (Suppl. 2): 1-19.
  9. Brinkley BR, Marcum JM, Welsh MJ, Dedman JR, Means AR. 1978. Regulation of spindle microtubule assembly/disassembly: Localization and possible functional role of calcium dependent regulator protein. In: Cell Reproduction: Daniel Mazia Dedicatory Volume. ER Dirksen, D Prescott, and CF Fox, eds., Academic Press, New York, pp. 299-314
  10. Means AR, Dedman JR, Welsh MJ, Marcum M, Brinkley BR. 1979. FSH and calcium as modulators of Sertoli cell differentiation and function. In: Ontogeny of Receptors and Molecular Mechanisms of Reproductive Hormone Action. TH Hamilton, JH Clark and WA Sadler, eds., Raven Press, New York, pp. 207-224.
  11. Welsh MJ, Dedman JR, Brinkley BR, Means AR: 1979. Tubulin and calmodulin: Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. J. Cell Biol. 81: 624-634
  12. Tash JS, Welsh MJ, Means AR: 1980. Protein kinase inhibitor as an intracellular marker of FSH action in the Sertoli cell. In: Testicular Development, Structure and Function. E Steinberger and A Steinberger, eds., Raven Press, New York, pp. 159-167
  13. Means AR, Welsh MJ, Dedman JR, Tash JS: 1980. FSH stimulation of protein kinase inhibitor: regulation of cellular metabolism. Adv. Cyclic Nucleotide Res. 12: 373-384.
  14. Means AR, Dedman JR, Tash JS, Tindall DJ, Van Sickle M, Welsh MJ. 1980. Regulation of the testis Sertoli cell by follicle stimulating hormone. Ann Rev. Physiol. 42: 59-70.
  15. Tash JS, Welsh MJ, Means AR: 1980. Protein inhibitor of cAMP-dependent protein kinase: Production and characterization of antibodies and intracellular localization. Cell 21: 57-65.
  16. Welsh MJ, Van Sickle M, Means AR: 1980. Possible involvement of cyclic AMP, calmodulin and the cytoskeleton in control of protein secretion by Sertoli cells. In: Testicular Development, Structure and Function. E Steinberger and A Steinberger, eds., Raven Press, New York, pp. 89-98
  17. Tash JS, Welsh MJ, Means AR: 1981. Regulation of protein kinase inhibitor by follicle stimulating hormone in Sertoli cells in vitro. Endocrinology 108: 427-434.
  18. Welsh MJ, Aster J, Ireland M, Alcala J, Maisel H: 1982. Calmodulin binds to chick lens gap junction protein in a calcium independent manner. Science 216: 642-644.
  19. Dedman JR, Welsh MJ, Kaetzel MA, Pardue RL, Brinkley BR: 1982. Localization of calmodulin in tissue culture cells. In: Calcium and Cell Function, vol. 3, WY Cheung, ed., Academic Press, New York, pp. 455-472.
  20. Bedows E, Rao KMK, Welsh MJ: 1983. Fate of microfilaments in measles virus and herpes simplex I virus-infected vero cells. Mol. Cell Biol. 3: 712-719.
  21. Zavortink M, Welsh MJ, McIntosh JR. 1983. The distribution of calmodulin in living mitotic cells. Exp. Cell Res. 149: 375-385.
  22. Welsh MJ. 1983. Localization of calmodulin and calmodulin acceptor sites by fluorescence methods. Meth. Enzymol. 102: 110-121.
  23. Aster JC, Welsh MJ, Brewer GJ and H Maisel. 1984. Identification of spectrin and protein 4.1-like proteins in mammalian lens. Biochem. Biophys. Res. Commun. 119: 726-734.
  24. Ellis M, Alousi S, Lawniczak J, Maisel H and Welsh M. 1984. Studies on lens vimentin. Exptl. Eye Res. 38: 195-202.
  25. Beattie PJ, Welsh MJ and MJ Brabec. 1984. The effect of 2-methoxy-ethanol and methoxyacetic acid on Sertoli cell lactate production and protein synthesis in vitro. Toxicol. Appl. Pharmacol. 76: 56-61.
  26. Welsh, MJ, Ireland ME and GJ Treisman: 1984. Sertoli cell adenylyl cyclase is stimulated by afactor associated with germ cells. Ann. N.Y. Acad. Sci. 438: 576-578.
  27. Welsh, MJ, ME Ireland and GJ Treisman. 1985. Stimulation of rat Sertoli cell adenylate cyclase by germ cells in vitro. Biol. Reprod. 33: 1050-1056.
  28. Ireland, ME, BB Rosenblum and MJ Welsh. 1986. 2-Dimensional gel analysis of Sertoli cell protein phosphorylation: Effect of short term exposure to follicle stimulating hormone. Endocrinology. 118: 526-532.
  29. McIntosh, JR, WM Saxton, DL Stemple, RJ Leslie and MJ Welsh. 1986. Dynamics of tubulin and calmodulin in the mammalian mitotic spindle. Ann. N.Y. Acad. Sci. 466: 566-579.
  30. Mali, P, MJ Welsh, J Toppari, KK Vihko and M Parvinen. 1986. Cell interactions in the rat seminiferous epithelium with special reference to the cellular distribution of calmodulin. Med. Biol. 63: 237-244.
  31. Batarseh, LI, MJ Welsh and MJ Brabec. 1986. Effect of lead acetate on Sertoli cell lactate production and protein synthesis in vitro. Cell Biol. Toxicol. 2: 283-292.
  32. Roberts-Lewis, JM, MJ Welsh and ME Gnegy. 1986. Chronic amphetamine treatment increases striatal calmodulin in rats. Brain Res. 384: 383-386.
  33. Ireland, ME and MJ Welsh. 1987. Germ cell stimulation of Sertoli cell protein phosphorylation. Endocrinology 120: 1317-1326.
  34. Welsh, MJ 1988. Localization of intracellular calcium-binding proteins. In: Calcium Binding Proteins, Vol. II, Biological Functions, M.P. Thompson, ed., CRC Press, Inc., Cleveland, OH, pp. 1-19.
  35. Welsh, MJ, M Ireland, J Metts, K Treinen and G Pittenger. 1988. The mechanism of Sertoli-germ cell interaction. Ann. N.Y. Acad. Sci. 513: 409-412.
  36. Stemple, DL, SC Sweet, MJ Welsh and JR McIntosh. 1988. Dynamics of a fluorescent calmodulin analog in the mammalian mitotic spindle at metaphase. Cell Motil. Cytoskel. 9: 231-242.
  37. Sobel, JS, EG Goldstein, JM Venuti and MJ Welsh. 1988. Spectrin and calmodulin in spreading mouse blastomeres. Devel. Biol. 126: 47-56.
  38. Sanchez, ER, T Redmond, LC Scherrer, EH Bresnick, MJ Welsh and WB Pratt. 1988. Evidence that the 90-kDa heat shock protein is associated with tubulin in L cell cytosol and intact PtK cells. Molec. Endocrinol. 2: 756-760.
  39. Sweet, SC and MJ Welsh. 1988. Calmodulin co-localization with cold-stable and nocodazole-stable microtubules in living cells. Eur. J. Cell Biol. 47: 88-93.
  40. Sweet, SC, CM Rogers and MJ Welsh. 1988. Calmodulin stabilization of kinetochore microtubule structure to the effect of nocodazole. J. Cell Biol. 107: 1334-1343.
  41. Sweet, SC, CM Rogers and MJ Welsh. 1989. Calmodulin is associated with microtubules forming in PtK cells upon release from nocodazole treatment. Cell Motil. Cytoskel. 12: 113-122.
  42. Pratt, WB, E Sanchez, E Bresnick, S Meshinchi and MJ Welsh. 1989. Interaction of the glucocorticoid receptor with the 90kDa heat shock protein: an evolving model of ligand-mediated receptor transformation and translocation. Cancer Res. 49(8): S2222-S2229.
  43. Welsh, MJ and SC Sweet. 1989. Calmodulin regulation of spindle function. In Mitosis, JS Hyams and BR Brinkley, eds. Academic Press, London. pp 203-240.
  44. Redmond, T, ER Sanchez, EH Bresnick, MJ Schlesinger, DO Toft, WB Pratt and MJ Welsh. 1989. Immunofluorescence co-localization of the 90-kDa heat shock protein and microtubules in interphase and mitotic cells. Eur. J. Cell Biol. 50: 66-75.
  45. Pratt, WB, T Redmond, ER Sanchez, EH Bresnick, S Meshinchi and MJ Welsh. 1989. Speculations on the role of the 90 kDa heat shock protein in glucocorticoid receptor transport and function. In: The Steroid/Thyroid Hormone Receptor Family and Gene Regulation, Gustafsson, JA, H Erickson and J Carlstedt-Duke, eds., Birkhauser Verlag, Basel. pp. 109-126.
  46. Clough, SR, MJ Welsh, AH Payne, CD Brown and MJ Brabec. 1990. Primary rat Sertoli and interstitial cells exhibit a differential response to cadmium. Cell Biol. Toxicol 6: 63-79.
  47. Sanchez, ER, M Hirst, LC Scherrer, H-Y Tang, MJ Welsh, JM Harmon, SS Simons, GM Ringold, and WB Pratt. 1990. Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90. J. Biol. Chem. 265: 20123-20130.
  48. Selinfreund, RH, SW Barger, MJ Welsh and LJ Van Eldik. 1990. Antisense inhibition of glial S100 production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation. J. Cell Biol. 111: 2021-2028.
  49. Sweet SC, ME Gnegy, and MJ Welsh. 1991. Presence of matrix-specific antibodies in affinity-purified polyclonal antibodies. J. Immunol. Meth. 136: 31-36.
  50. Sklar, MD, E Thompson, MJ Welsh, M Liebert, J Harney, HB Grossman, M Smith and EV Prochownik. 1991. Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells. Molec. Cell. Biol. 11: 3699-3710.
  51. Gnegy, ME, K Hewlett, S Yee, and MJ Welsh. 1991. Alterations in calmodulin content and localization in areas of rat brain after repeated intermittent amphetamine treatment. Brain Res. 562: 6-12.
  52. Welsh, MJ and ME Ireland. 1992. The second messenger pathway for germ cell-mediated stimulation of Sertoli cells. Biochem. Biophys. Res. Commun. 184: 217-224.
  53. Pittenger, GL, RR Gilmont, and MJ Welsh. 1992. Induction of the low molecular weight heat-shock protein (hsp27) in rat Sertoli cells and evidence for the identity of hsp27 with a germ cell-responsive phosphoprotein. Endocrinology 130: 3207-3215.
  54. Newton, SC, MJ Welsh, and A Bartke. 1992. Effect of age, photoperiod, and follicle stimulating hormone on lactate production by cultured Sertoli cells from Siberian hamsters (Phodopus sungorus). J. Reprod. Fert. 95: 87-95.
  55. Redmond, T, R Jove, BK Brott, and MJ Welsh. 1992. Localization of the viral and cellular src Kinases to perinuclear vesicles in fibroblasts. Cell Growth Differ. 3: 567-576.
  56. Van Eldik, LJ, SW Barger, and MJ Welsh. 1992. Antisense approaches to the function of glial cell proteins. Ann. N.Y. Acad. Sci. 660 (Antisense Strategies):219-230.
  57. Hew, K-W, WA Ericson, and MJ Welsh. 1993. A single low cadmium dose causes failure of spermiation in the rat. Toxicol. Appl. Pharm. 121:15-21.
  58. Hew, K-W, GL Heath, AH Jiwa, and MJ Welsh. 1993. Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells. Biol. Reprod. 49: 840-849.
  59. Perdew, GH, N Hord, CE Hollenbeck, and MJ Welsh. 1993. Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells. Exptl. Cell Res. 209: 350-356.
  60. Rees, RS, GJ Kingman, B Cashmer, RR Gilmont, C Reeves, MJ Welsh, and DJ Smith. 1994. DT Diaphorase: Increased enzyme activity and mRNA expression in oxidant stress of skin. J. Surg. Res. 56: 1-5.
  61. Pratt, WB and MJ Welsh. 1994. Chaperone functions of the heat shock proteins associated with steroid receptors. Seminars in Cell Biology 5: 83-93.
  62. Czar, MJ, JK Owens-Grillo, AW Yem, KL Leach, MR Deibel, MJ Welsh, and WB Pratt. 1994. The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor. Molec. Endocrinol. 8: 1731-1741.
  63. Wu, W and MJ Welsh. 1995. A method for purification of DNA species by high speed centrifugation of agarose gel slices. Anal. Biochem. 229: 350-352.
  64. Czar, MJ, RH Lyons, MJ Welsh, M Renior, and WB Pratt. 1995. Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorti-coid receptor from the cytoplasm to the nucleus. Molec. Endocrinol. 9: 1549-1560.
  65. Yamada, H., J Strahler, MJ Welsh, and KN Bitar. 1995. Activation of MAP kinase and interaction with hsp27 in bombesin induced contraction of gastrointestinal smooth muscle. Am. J. Physiol. 269: G683-G691.
  66. Gilmont, RR, A Dardano, JS Engle, BS Adamson, MJ Welsh, T Li, DG Remick, DJ Smith, and RS Rees. 1996. TNF-alpha potentiates oxidant and reperfusion-induced endothelial cell injury. J. Surg. Res. 61: 175-182.
  67. Wu, W and MJ Welsh. 1996. Rapid method for coomassie blue staining and destaining of polyacrylamide gels. BioTechniques 20: 386-388.
  68. Welsh MJ, W Wu, M Parvinen, and RR Gilmont. 1996. Variation in expression of hsp27 messenger RNA during the cycle of the seminiferous epithelium and co-localization of hsp27 and microfilaments in Sertoli cells of the rat. Biol. Reprod. 55: 141-151.
  69. Smoyer, WE, A Gupta, P Mundel, JD Ballew, and MJ Welsh. 1996. Altered expression of glomerular hsp27 in experimental nephrotic syndrome. J. Clin. Invest. 97: 2697-2704.
  70. Czar MJ, MJ Welsh, and WB Pratt. 1996. Immunofluorescence localization of the 90-kDa heat shock protein to cytoskeleton. Eur. J. Cell Biol. 70: 322-330.
  71. Mirkes PE, Little SA, L Cornel, MJ Welsh, T-N Ngo Laney, FH Wright. 1996. Induction of heat shock protein 27 (hsp27) in rat embryos exposed to hyperthermia. Molec. Reprod. Devel. 25: 276-284.
  72. Wu, W and MJ Welsh. 1996. Expression of the 25-kDa heat-shock protein (HSP27) correlates with resistance to the toxicity of cadmium chloride, mercuric chloride, cis-platinum(II)-diammine dichloride, or sodium arsenite in mouse embryonic stem cells transfected with sense or antisense. Toxicol. Appl. Pharmacol. 141: 330-339.
  73. Smoyer, WE, P Mundel, A Gupta, and MJ Welsh. 1997. Podocyte alpha-actinin induction precedes foot process effacement in experimental nephrotic syndrome. Am. J. Physiol. 273: F150-F157.
  74. Welsh, MJ and M Gaestel. 1998. Small heat shock protein family: function in health and disease. In: Stress of Life from Molecules to Man. (ed.: P. Csermely) Annals of New York Academy of Sciences, vol. 851, 1-19.
  75. Galigniana, MD, JL Scruggs, J Herrington, MJ Welsh, C Carter-Su, PR Housley and WB Pratt. 1998. Heat Shock Protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton. Molec. Endocrinol. 12: 1903-1913.
  76. Benndorf, R, RF Ransom, RR Gilmont, K Hayess and MJ Welsh. 1998. Inhibition of small heat shock protein (HSP25) kinase (MAPKAP kinase-2). Emerging Therapeutic Targets 2: 147-149.
  77. Liu, C., and M.J. Welsh. 1999. Identification of a Site of Hsp27 Binding with Hsp27 and (B-Crystallin as Indicated by the Yeast Two-Hybrid System. Biochem. Biophys. Res. Commun. 255:256-261.
  78. Ibitayo, A.I., J. Stadick, S. Tuteja, O. Louis-Jacques, H. Yamada, G. Groblewski, M.J. Welsh and K.N. Bitar. 1999. Involvement of hsp27 in signal transduction and association with contractile proteins in smooth muscle cells. Am. J. Physiol. 277: G445-454
  79. Schafer, C., P. Clapp, M.J. Welsh, R. Benndorf and J.A. Williams. 1999. Hsp27 expression and phosphorylation regulates cholecystokinin-induced changes in the actin cytoskeleton in CHO-CCK-A cells. Am. J. Physiol. 277: C1032-1043

  80. Smoyer, W.E., R.F. Ransom, R.C. Harris, M.J. Welsh, G. Lutsch and R. Benndorf. 2000. Ischemic acute renal failure induces differential expression of small heat shock proteins. J. Am. Soc. Nephrol. 11:211-221.

  81. Liu, C., R.R. Gilmont, R. Benndorf and M.J. Welsh. Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27. J. Biol. Chem. 275: 18724-18731.

  82. Benndorf, R, X Sun, RR Gilmont, KJ Biederman, MP Malloy, CW Goodmurphy, H Cheng, PC Andrews and MJ Welsh.  2001.  Hsp22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated hsp27 (3Dhsp27).  J. Biol. Chem. 276:26753-26761.
  83. Jia, Y, RF Ransom, M. Shibanuma, C. Liu, MJ Welsh and WE Smoyer.  2001.  Identification and characterization of Hic-5/ARA55 as an hsp27-binding protein.  J. Biol. Chem. 276:39911-39918

    84. Accepted in Press or Submitted Manuscripts:

  84. Hirano, S, X Sun, RF Ransom, MJ Welsh, WE Smoyer, EA Shelden and R Benndorf.  Cadmium-induced contraction of mesangial cells involves p38/HSP25-signaling.
    (accepted by FASEB Journal)
  85. Augustine, K.A., Q. Zhang, J.Leonard, R. Lawton, M.J. Welsh.  A study of vehicles for dosing rodent whole embryo culture with non-aqueous soluble compounds. 
    (sumitted to Reproductive Toxicology.

    Books:

  1. Methods in Gene Biotechnology, by W Wu, MJ Welsh, PB Kaufman and HH Zhang. CRC Press, Boca Raton, FL. pp 406. 1997.

    Genebank Submissions:

  1. Gilmont, RR and MJ Welsh. 1992. Sequence of a complete rat hsp27 cDNA. #M86389.
  2. Liu, C. and M.J. Welsh. 1999. Complete cDNA sequence of a Sertoli cell hsp27-binding protein, PASS1. #AF168362.
  3. Benndorf, R, R Gilmont, C Liu and MJ Welsh.  2000.  Complete cDNA coding sequence of human    hsp22.  #AF250138.
  4. Goodmurphy, C, R Benndorf and MJ Welsh.  2000.  Complete cDNA coding sequence of mouse     hsp22.  #AF250139.
  5. Cheng, H, R Benndorf and MJ Welsh. 2000.  Complete cDNA  coding sequence of rat hsp22. #AF314540.
  6. Jia, Y, R Ransom, W Smoyer and MJ Welsh.  2000.  Partial cDNA coding sequence of rat hic-5/ARA55. #AF314960.
  7. Jia, Y, R Ransom, MJ Welsh and W Smoyer.  2000.  Complete cDNA coding sequence of rat sop2p.  #AF315378.

    Abstracts:

  1. Welsh, MJ, and JP Wiebe. Rat Sertoli cells: A rapid method of obtaining viable cells. 17th ann. meeting of Canadian Fed. of Biol. Societies. Hamilton, Ontario, Canada, June, 1974.
  2. Wiebe, JP, MJ Welsh, B Eckstein, and BR Chin-Yee. In vitro androgen biosynthesis in rat Sertoli cells. International Symposium on Androgens and Antiandrogens. Milan, Italy, April 1976.
  3. Welsh, MJ, and JP Wiebe. Metabolism of C19-steroids by Sertoli cells from rats 6 to 60 days old and the effect of FSH in vitro. IV NIH Workshop on the Testis. Toronto, Ontario, Canada, May 1977.
  4. Means, AR, BR Brinkley, JR Dedman, and MJ Welsh. Changes in the cytoskeleton and associated proteins during Sertoli cell maturation. IV NIH Workshop on the Testis. Toronto, Ontario, Canada, May, 1977.
  5. Welsh, MJ, JR Dedman, BR Brinkley, AR Means. Mechanism of follicle stimulating hormone (FSH) action: Interaction of cyclic nucleotides, Ca2+ and microfilaments in the testis Sertoli cell. Third International Symposium on Cyclic Nucleotides, New Orleans, July, 1977.
  6. Welsh, MJ, JR Dedman, BR Brinkley, and AR Means. Calcium dependent regulator protein associated with the mitotic apparatus of mammalian cells. 17th annual meeting of American Society for Cell Biology. San Diego, November, 1977.
  7. Marcum, JM, JR Dedman, MJ Welsh, BR Brinkley, and AR Means. Regulation of microtubule assembly-disassembly by calcium dependent regulator protein. American Society of Biological Chemists. Atlanta, April, 1978.
  8. Welsh, MJ, JR Dedman, S Cox, BR Brinkley, and AR Means. Calcium dependent regulator protein: A dynamic component of the mitotic apparatus. Cold Spring Harbor Symposium on Cell Motility, Cold Spring Harbor, New York. May, 1978.
  9. Tash, JS, MJ Welsh, and AR Means. Protein kinase inhibitor: Specific stimulation by FSH in Sertoli cells in vitro. VI NIH Workshop on the Testis. Houston, April 1979.
  10. Welsh, MJ, M Van Sickle, and AR Means. The effects of FSH on isolated Sertoli cells. VI NIH workshop on the Testis. Houston, April, 1979.
  11. Tash, JS, MJ Welsh, and AR Means. Specific stimulation by FSH of protein kinase inhibitor (PKI) in Sertoli cells in vitro. Endocrine Society Meetings, Anaheim. June, 1979.
  12. Tash, JS, MJ Welsh, JR Dedman, and AR Means. Protein kinase inhibitor: Characterization of antibody and subcellular localization on microtubules by indirect immunofluorescence. 19th meeting of American Society for Cell Biology. Toronto, Canada, November, 1979.
  13. Lin, CT, JR Dedman, MJ Welsh, BR Brinkley, and AR Means. Immunoelectron localization of calmodulin in the mitotic apparatus. 19th annual meeting of American Society for Cell Biology. Toronto, Canada, November, 1979.
  14. Welsh, MJ, J Aster, M Ireland, J Alcala, and H Maisel. Calmodulin and Gap Junctions: Localization of calmodulin and calmodulin binding sites in chick lens cells. 21st annual meeting of American Society for Cell Biology, Anaheim. November, 1981.
  15. Welsh, MJ, M Johnson, M Zavortink, and JR McIntosh. Microinjection of calmodulin- rhodamine into living cells: Localization in the mitotic apparatus. 21st annual meeting of American Society for Cell Biology, Anaheim. November, 1981.
  16. Maisel, J., M. Welsh, M. Ireland, J. Aster, and J. Alcala. Calmodulin and Gap Junctions: Localization of calmodulin and calmodulin binding sites in chick lens cells. ARVO, 1982.
  17. Alcala, J, M Welsh, and H Maisel. Calmodulin: Calcium binding protein of the crystalline lens. Fifth International Congress of Eye Research, Eindhoven, The Netherlands, 1982.
  18. Bedows, E, KMK Rao, MJ Welsh, and PR Knight. Effect of Halothane on the cellular cytoskeletal system. American Society of Anesthesiologists, 1982.
  19. Bedows, E, RE Hinkley, MJ Welsh, and PR Knight. Membrane requirement for halothane- induced microfilament disruption. American Society of Anesthesiologists, 1983.
  20. Welsh, MJ, ME Ireland, and GJ Treisman. Sertoli cell adenylyl cyclase is stimulated by a factor associated with germ cells. Eight NIH Workshop on the Testis, Bethesda, MD, Oct. 1983.
  21. Welsh, M.J, and GJ Treisman. Sertoli cell adenylate cyclase is stimulated by a factor associated with germ cells. 23rd Annual Meeting of The American Society for Cell Biology, San Antonio, Texas, November, 1983.
  22. Beattie, P, G Miller, MJ Welsh, MJ Brabec. Dibromochloropropane and methoxyacetic acid alter lactate metabolism by isolated rat spermatocytes. Society for the Study of Reproduction, Annual meeting, Laramie, WY., 1984.
  23. Welsh, MJ, GJ Treisman, and ME Ireland. Germ cell activation of Sertoli cell adenylyl cyclase. Third European Testis Workshop, Lyon, France, April, 1984.
  24. Beattie, PJ, MJ Welsh, and MJ Brabec. Methoxyacetic acid inhibits lactate accumulation rat in isolated Sertoli cells. Third European Testis Workshop, Lyon, France, April, 1984.
  25. Beattie, PJ, MJ Welsh, and MJ Brabec. Effect of methoxyacetic acid on isolated Sertoli cells. FASEB, St. Louis, MO, 1984.
  26. Roberts, D, PR Knight, and MJ Welsh. Intracellular pH changes in the presence of halothane. American Society of Anesthesiologists, New Orleans, October, 1984.
  27. Treisman, G, R Lawton, S Sweet, and M. Welsh. Diazopyruvoyl p-nitrophenylester: A new photoactivatable cross-linking reagent. FASEB conference on Calcium and Cell Function, Saxton's River, VT., June, 1984.
  28. Roberts-Lewis, JM, MJ Welsh, and ME Gnegy. Detection of amphetamine-induced changes in striatal calmodulin with a simple, inexpensive radioimmunoassay. Society for Neuroscience, November, 1984.
  29. Miller, GE, MJ Welsh, and MJ Brabec. Alteration of lactate metabolism in Sertoli cells and spermatocytes by 1,2-dibromo-3-chloropropane. Society for Toxicology, San Diego, 3/85.
  30. Sweet, S, and MJ Welsh. Fluorescently labeled calmodulin microinjected into living cells associates with cold-stable microtubules. International Congress on Fluorescence Methods in Biomedical Science, Pittsburg, PA, April, 1985.
  31. Mali, P, MJ Welsh, and M Parvinen. Cellular distribution of calmodulin during rat spermatogenesis. XV Acta Endocrinologica Cong., Helsinki, August 1985.
  32. Stemple, DL, MJ Welsh, WM Saxton, and JR McIntosh. Calmodulin dynamics in mammalian mitotic spindles. Intl. Conf. Application Fluoresc. Biomed. Sci., Pittsburg, PA, April, 1985.
  33. Ireland, ME, BB Rosenblum, and MJ Welsh. Mechanisms of Sertoli cell hormone response. Symposium on Regulatory Factors in Development and Reproduction, Ann Arbor, MI, 1985.
  34. Welsh, MJ, and ME Ireland. Germ cells rapidly affect phosphorylation of specific proteins in cultured Sertoli cells by a calcium-dependent mechanism. American Society of Cell Biology, Atlanta, November, 1985, J. Cell Biol. 101:372a.
  35. Ireland, ME, BB Rosenblum, and MJ Welsh. Phosphorylation of proteins in cultured Sertoli cells acutely stimulated by FSH, dibutyryl cAMP, ionophore A23187 and the phorbol ester TPA. American Society of Cell Biology, Atlanta, November, 1985, J. Cell Biol. 101:380a.
  36. Sweet, SC, and MJ Welsh. Calmodulin co-localizes with cold-stable and nocodazole stable microtubules in living cells. American Society of Cell Biology, Atlanta, November, 1985, J. Cell Biol. 101:147a.
  37. Pittenger, GL, ME Ireland, and MJ Welsh. Differentiation of Sertoli cells is reflected in the patterns of calcium-dependent protein phosphorylation. University of Michigan Biomedical Research Council Forum, Ann Arbor, MI, 1986.
  38. Clough, SR, MJ Welsh, and MJ Brabec. Biochemical response of primary rat Sertoli cell cultures to cadmium. Society of Toxicology, 1986.
  39. Pavittranon, S, MJ Welsh, and MJ Brabec. Methoxyacetic acid stimulates carbohydrate metabolism by Sertoli cell in vitro. Society of Toxicology, 1986.
  40. Miller, GE, PJ Beattie, MJ Welsh, and MJ Brabec. Comparative cytotoxicity of 1,2- dibromo-3-chloropropane (DBCP) and proposed metabolites to isolated spermatocytes. Society of Toxicology, 1986.
  41. Batarseh, LI, MJ Welsh, and MJ Brabec. Lead acetate inhibits glucose utilization in Sertoli cells and lactate utilization in germ cells in vitro. Society of Toxicology, 1986.
  42. Welsh, MJ, ME Ireland, J Metts, K Treinen, and G Pittenger. The mechanism of Sertoli- germ cell interaction. 1986 Testis Workshop: Cell Biology of the Testis and Epididymis. Nashville, TN, Oct. 14-17, 1986.
  43. Bataresh, LI, MJ Brabec, and MJ Welsh. Lead acetate stimulates protein phosphorylation in Sertoli cells in vitro. American Society for Cell Biology, Washington, D.C., 1986, J. Cell Biol., 103:481a.
  44. Sweet, SC, and MJ Welsh. Microinjection of calmodulin stabilizes kinetochore microtubules to nocodazole treatment in living cells. American Society for Cell Biology, Washington, D.C., 1986, J. Cell Biol. 103:140a.
  45. Metts, J, and MJ Welsh. Differential centrifugation analysis of subcellular distribution of substrates of cyclic AMP- dependent calcium/calmodulin-dependent and calcium/phospholipid-dependent protein kinases in rat Sertoli cells. Society for the Study of Reproduction, July 1987.
  46. Sweet, SC, CM Rogers, and MJ Welsh. Calmodulin binds to the mitotic apparatus in a calcium-independent manner. American Society for Cell Biology, October, 1987.
  47. Sanchez, ER, LC Scherre, T Redmond, MJ Welsh, and WB Pratt. Evidence that the glucocorticoid receptor in L cell cytosol can be polymerized into microtubules. UCLA Symp. Molec. Cell. Biol., Keystone, CO, April, 1988.
  48. Bresnick, EH, T Redmond, ER Sanchez, MJ Welsh, and WB Pratt. Demonstration that the 90-kDa heat shock protein is associated with tubulin in L cell cytosol and in intact PtK cells. UCLA Symp. Molec. Cell Biol., Keystone, CO, April, 1988.
  49. Welsh, MJ, GL Pittenger, SR Clough, L Batarseh, and MJ Brabec. The 26-kDa Sertoli cell protein whose phosphorylation is affected by germ cells is also a stress-induced protein. Soc. for the Study of Reproduction, Seattle, 1988. Biol. Reprod. 38(1):141a.
  50. Sweet, SC, CM Rogers, and MJ Welsh. Calmodulin is associated with microtubules forming in PtK cells upon release from nocodazole treatment. American Society for Cell Biology, San Francisco, Jan., 1989.
  51. Pratt, WB, T Redmond, ER Sanchez, LC Scherrer, EH Bresnick and MJ Welsh. Evidence that the 9S glucocorticoid receptor-hsp90 complex is derived from cytoskeleton. Endocrine Society meetings, 1989.
  52. Redmond, T, ER Sanchez, WB Pratt, and MJ Welsh. Immunofluorescence localization of the 90-kDa heat shock protein to tubulin-containing structures in interphase and mitotic cells. American Society for Cell Biology, San Francisco, Jan. 1989. J. Cell Biol. 107(6):459a.
  53. Pittenger, GL, SR Clough, M Brabec, and MJ Welsh. A rat Sertoli cell protein posphorylated in response to germ cells is a low molecular weight heat shock protein. American Society for Cell Biology, San Francisco, Jan., 1989. J. Cell Biol. 107(6): 170a.
  54. Hew, KW, T Redmond, SC Sweet, JS Shayevitz, and MJ Welsh. Volatile anesthetic (halothane) induction of the stress response in endothelial cells. American Society for Cell Biology meetings, Nov., 1989, Houston, TX.
  55. Pittenger, GL, and MJ Welsh. Characterization of an antibody that recognizes a low molecular weight heat shock protein (hsp27) in rat Sertoli cells. American Society for Cell Biology meetings, Nov., 1989, Houston, TX.
  56. Shayevitz, JR, KW Hew, MJ Welsh, J Varani, and PR Knight. Volatile anesthetics enhance hydrogen peroxide-mediated injury, increases in [Ca2+]i, and morphological changes in endothelial cells. American Society for Cell Biology meeting, Nov., 1989, Houston, TX.
  57. Gilmont, RR , and MJ Welsh. Molecular cloning of the rat low molecular weight heat-shock protein hsp27. Society for the Study of Reproduction meetings, Vancouver, Canada, July 1991.
  58. Olson, AD, and MJ Welsh. A time-lapse video study of multicellular organization of IEC-6 cells on reconstituted basement membrane. American Society for Cell Biology meetings, Dec., 1991, Boston, MA.
  59. Batarseh, LI, MJ Welsh, and MJ Brabec. Expression of heat-shock proteins (hsp) mRNA in Sertoli cell cultures exposed to cadmium. Abstract 1711, 31st meeting of the Society of Toxicology, Seattle, Feb. 1992.
  60. Brabec, MJ, LI Batarseh, MJ Welsh. Induction of heat-shock proteins (HSPs) in Sertoli cells by cadmium. Presented at: Metabolic and Molecular Injury by Metals: Quantitation and Significance, 1992 World Congress on Cell and Tissue Culture, Washington, D.C. June, 1992.
  61. Hew, KW, RR Gilmont, and MJ Welsh. Cadmium causes stage specific damage in the seminiferous epithelium. 32nd meeting, Teratology Society, Boca Raton, FL, June, 1992. Teratology 45: 500a.
  62. Rees, R, L Tiedong, B Cashmer, R Gilmont, and MJ Welsh. The role of TNF in lung injury following ischemia/reperfusion of the rat limb. Society of University Surgeons, 1992.
  63. Jiwa, AH, K-W Hew, G Heath, and MJ Welsh. Observations on the 3-dimensional distribution of microfilaments in seminiferous tubules of the rat: a singe low cadmium dose disrupts Sertoli cell microfilaments at stage VIII of spermatogenesis. The Academy of Environmental Biology meeting "Toxicology, Conservation and Biodiversity", Meerut, India, Dec. 1992.
  64. Sun, D, L Batarseh, M Welsh, and M Brabec. Dibromochloropropane (DBCP), methoxyacetate (MA) and meta-dinitrobenzene (mDNB) induce heat shock protein 27 mRNA in Sertoli cell cultures. Soc. Toxicology, 32nd Meeting, New Orleans, March 1993.
  65. Welsh, MJ, and RR Gilmont. Hsp27 co-localization with microfilaments in Sertoli cells in culture, in whole mount seminiferous tubules, and in frozen sections of testis of the rat. American Society for Cell Biology meeting, New Orleans, Dec. 1993.
  66. Welsh, MJ, K-W Hew, GL Heath, MJ Brabec, and RR Gilmont. Hsp27: a possible target for toxicants in the testis. Soc. Toxicology, 33rd meeting, Dallas, March 1994.
  67. Smoyer, WE, J Strahler, RC Wiggins, and MJ Welsh. Altered expression of hsp27 in experimental nephrotic syndrome. American Society for Cell Biology meeting 1994, San Francisco, CA.
  68. Welsh, MJ, C DeGuzman, R Gilmont, Y Jia, M Parvinen, and W Wu. Hsp27 in Sertoli cells: Germ cell-stimulated hsp27 phosphorylation, mRNA levels during spermatogenesis and hsp27 co-localization with microfilaments. Keystone Symposium, Feb-March 1995, Santa Fe, NM.
  69. Smoyer, WE, TA Ellis, J Strahler, RC Wiggins, and MJ Welsh. Altered expression of hsp27 in experimental nephrotic syndrome. Keystone Symposium, Feb-March 1995, Santa Fe. NM.
  70. Smoyer, WE, A Gupta, PV Cherian, and MJ Welsh. Altered expression of hsp27 in experimental nephrotic syndrome. American Society of Nephrology, November 5-8, 1995. Anaheim, CA.
  71. Smoyer, WE, A Gupta, DA Linseman, JD Ballew, MJ Welsh. Enhanced hsp27 expression and phosphorylation in experimental nephrosis. Midwest Stress Response and Chaperone Meeting, Evanston, IL 1/96.
  72. Wu, W and MJ Welsh. Expression of hsp27 correlates with resistance to metal toxicity in mouse embryonic stem cells transfected with sense or antisense hsp27 cDNA. Midwest Stress Response and Chaperone Meeting, Evanston, IL 1/20/96.
  73. Wu, W and MJ Welsh. Expression of hsp27 correlates with resistance to metal toxicity in mouse embryonic stem cells transfected with sense or antisense hsp27 cDNA. Society of Toxicology, March 10-14, 1996, Anaheim, CA
  74. Smoyer, WE, A Gupta, P Mundel, J Ballew, MJ Welsh. Enhanced glomerular hsp27 expression and phosphorylation in experimental nephrotic syndrome. Cold Spring Harbor Laboratory Meeting on: Molecular Chaperones and the Heat Shock Response. May 1-5, 1996, Cold Spring Harbor, NY.
  75. Smoyer, WE, A Gupta, MJ Welsh. Enhanced expression of glomerular cytoskeleton- associated proteins during induction of podocyte foot process effacement. American Society of Nephrologists, 29th annual meeting, New Orleans, Nov. 3-6, 1996.
  76. Welsh, MJ, RR Gilmont, C DeGuzman, JD Ballew, and W Wu. Expression and localization of hsp27 in the testis. Stress Proteins in Reproductive Toxicology Workshop, sponsored by the Environmental Protection Agency, Research Triangle Park, NC, Nov. 1996.
  77. Liu C and MJ Welsh. Differences in interaction between hsp27 and (B-cystallin as revealed by the yeast two-hybrid system. American Society for Cell Biology meeting, San Francisco, Dec. 1996
  78. Liu C and MJ Welsh. Differences in interaction between hsp27 and (B-cystallin as revealed by the yeast two-hybrid system. Second Annual Midwest Stress Response and Chaperone Meeting, Chicago, IL 1/18/97.
  79. Benndorf, R, J Pritts, G Lutsch, R Vetter and MJ Welsh. Small stress proteins in cardiac and skeletal muscle. Second Annual Midwest Stress Response and Chaperone Meeting, Chicago, IL 1/18/97.
  80. Welsh, MJ, W Wu, JD Ballew. An inducible system for control of hsp27 expression in transgenic mice. Symposium on Mechanisms of Developmental Toxicology: Altered Gene Expression, Teratology Society meeting, Palm Beach, FL, June 21-26, 1997.
  81. Welsh, MJ and C Liu. Hsp25 binding to (B-crystallin and other proteins as revealed by the yeast two-hybrid system. International Congress of Stress, Budapest, Hungary, July 1-5, 1997.
  82. Benndorf, R, G Lutsch, J Pritts, R Vetter, U Offhaus, I Schimke and MJ Welsh. Hsp25 and (B-crystallin in cardiac and skeletal muscles. International Congress of Stress, Budapest, Hungary, July 1-5, 1997.
  83. Tanigawa, S, R Rees, M Welsh and R Gilmont. Differential tissue expression and phosphorylation of hsp27 in LPS treated rats. American Society for Cell Biology meeting, Dec, 1997. Molec. Biol. Cell 8(supplement):367a.
  84. Liu, C and MJ Welsh. Cloning and characterization of a novel hsp27-binding protein. American Society for Cell Biology meeting, Dec, 1997. Molec. Biol. Cell 8(supplement):367a
  85. Brabec, MJ, J Murray, C Huber, EL Harper and MJ Welsh. Toxicity of dinitrobenzenes toward Sertoli cell cultures. Society of Toxicology, Seattle, WA, March 1-5, 1998.
  86. Benndorf, R., R. Gilmont, N. Slawny, C. Liu and M.J. Welsh. HSP22, a new mammalian heat-shock protein, interacts with the 3D mutant (mimic of phosphorylated) HSP27. 5th Annual Stress Response and Chaperones meeting, Evanston, IL. Jan 15, 2000.
  87. Augustine, KA, Q Zhang and MJ Welsh. A study of vehicles for dosing cultured rodent embryos with non-aqueous soluble compounds. March, 2000. Society of Toxicol., Tox. Sci. 54: 297a.
  88. Benndorf, R., R. Gilmont, N. Slawny, C. Liu and M.J. Welsh. HSP22, a new mammalian small heat shock protein, interacts with the phosphorylated form of hsp27. FASEB, San Diego, CA, April, 2000.
  89. Benndorf, R., , R. Gilmont, N. Slawny, C. Liu and M.J. Welsh.  HSP22, a new mammalian small heat shock protein, interacts with the 3D mutant (mimic of phosphorylation) hsp27.  Cold Spring Harbor Symposium, May, 2000.
  90. Jia, Y., M.J. Welsh, R.F. Ransom, C. Liu and W.E. Smoyer.  Identification, characterization and functional analysis of Hic-5 as a new glomerular Hsp27-binding protein.  Annual meeting of the Society of Nephrology, Toronto, CA  Oct., 2000.
  91. Jia, Y., R.F. Ransom, C. Liu, W.E. Smoyer and M.J. Welsh.  Identification and analysis of Hic-5/ARA55 as an Hsp27-binding protein.  Sixth Annual Midwest Stress Response and Chaperone Meeting, Chicago, Jan., 2001.
  92. Jia Y., R.F. Ransom, W.E. Smoyer, and M.J. Welsh.  A Role for Hic-5 in Focal Adhesion Formation and in Hsp27-Mediated Actin Filament Stabilization.  Seventh Annual
    Midwest Stress Response and Chaperone Meeting, Evanston, IL, Jan., 2002.
  93. Sun, X., R.R. Gilmont, K.J. Biederman, M.P. Malloy, C.W. Goodmurphy, H. Cheng, P.C. Andrews, M.J. Welsh, R. Benndorf.  Mammalian hsp22: Interaction with other small hsps and in vitro phosphorylation.  Seventh Annual Midwest Stress Response and Chaperone Meeting, Evanston, IL, Jan., 2002.
  94. Welsh, M.J., R. Ransom, W Smoyer and Y. Jia.  A role for hic-5 in focal adhesion formation and in hsp27-mediated actin filament stabilization.  Society for Toxicology, Nashville, March 2002.
  95. Benndorf, R.,, X. Sun, R.R. Gilmont, K.J. Biederman, M.P. Malloy, C.W. Goodmurphy, H. Cheng, P.C. Andrews, M.J. Welsh,.  Mammalian hsp22: Interaction with other small hsps and in vitro phosphorylation.  Cold Spring Harbor Symposium on Heat Shock Proteins and Stress Response.  May, 2002.
  96. Hirano, S., X. Sun, R.F. Ransom, M.J. Welsh, W.E. Smoyer, E.A, Shelden and R. Benndorf.  Cadmium-induced contraction of mesangial cells involves P38MAPK/Hsp25 signaling.  Eighth Annual Midwest Stress Response and Chaperone Meeting, Evanston, IL, Jan., 2003.
  97.  J.-M. Fontaine, J.S. Rest, M.J. Welsh and R. Benndorf.  The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins.  Eighth Annual Midwest Stress Response and Chaperone Meeting, Evanston, IL, Jan., 2003.
  98. X. Sun, M.J. Welsh and R. Benndorf.  Identification of interacting domains of hsp22 with other small heat shock proteins in homo- and hetero-oligomeric dimers.  Eighth Annual Midwest Stress Response and Chaperone Meeting, Evanston, IL, Jan., 2003.

Last updated January, 2003.