Publications (Google Scholar)

We are developing new immunotherapies and vaccines by applying the principles of pharmaceutics, drug delivery, and biomedical engineering.

Lab News

2021

103. Sun X, Zhang Y, Li J, Park KS, Han K, Zhou X, Xu Y, Nam J, Xu J, Shi X, Wei L, Lei YL, Moon JJ§. Amplifying STING Activation by Cyclic Dinucleotide-Manganese Particles for Local and Systemic Cancer Metalloimmunotherapy. doi.org/10.1038/s41565-021-00962-9 , 2021, Nature Nanotech. Link PDF


102. Han K, Nam J, Xu J, Sun X, Huang X, Animasahun O, Achreja A, Joen JH, Pursley B, Kamada N, Chen GY, Nagrath D, Moon JJ§. Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel. doi: 10.1038/s41551-021-00749-2, 2021, Nature Biomedical Eng. Link PDF


101. Najafabadi AH, Abadi ZI, Aikins ME, Foulds KE, Donaldson MM, Yuan W, Okeke EB, Nam J, Xu Y, Weerappuli P, Hetrick T, Adams D, Lester PA, Salazar AM, Barouch DH, Schwendeman A, Seder RA, Moon JJ§. Vaccine nanodiscs plus polyICLC elicit robust CD8 T cell responses in mice and non-human primates. 337, 168-178, 2021, Journal of Controlled Release. Link PDF


100. Moon JJ§, De Geest B, Sun X. Next Generation Immunotherapies – Emerging Strategies for Immune Modulation against Cancer, Infections, and Beyond. doi.org/10.1002/adtp.202100157, 2021, Advanced Therapeutics. (Editorial) Link PDF


99. Nam J, Son S, Park KS, Moon JJ§. Photothermal therapy combined with neoantigen cancer vaccination for effective immunotherapy against large established tumors and distant metastasis. 2100093, 2021, Advanced Therapeutics. Link PDF


98. Park KS*, Nam J*, Son S, Moon JJ§. Personalized combination nano-immunotherapy for robust induction and tumor infiltration of CD8+ T cells, 274, 120844, 2021, Biomaterials. Link PDF


97. Alghamri MS, McClellan BL, Hartlage MS, Haase S, Faisal SM, Thalla R, Dabaja A, Banerjee K, Carney SV, Mujeeb AA, Olin MR, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments. 12:680021, 2021, Front. Pharmacology. Link PDF


96. Park KS, Sun X, Aikins ME, Moon JJ§. Non-viral COVID-19 vaccine delivery systems, 169, 137-151, 2021, Advanced Drug Delivery Reviews. Link PDF


95. Nam J, Son S, Park KS, Moon JJ§. Modularly programmable nanoparticle vaccine based on polyethyleneimine for personalized cancer immunotherapy, 8, 5:2002577, 2021, Advanced Science. Link PDF


94. Arai Y, Choi B, Kim BJ, Park S, Park H, Moon JJ, Lee SH. Cryptic ligand on collagen matrix unveiled by MMP13 accelerates bone tissue regeneration via MMP13/Integrin α3/RUNX2 feedback loop, S1742-7061, 21, 00137-9, 2021, Acta Bio. Link PDF


93. Yuan W, Yu B, Yu M, Kuai R, Morin EE, Wang H, Hu D, Zhang J, Moon JJ, Chen YE, Guo Y, Schwendeman A. Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport. 329:361-371, 2021, Journal of Controlled Release. Link PDF


92. Park KS, Bazzill JD, Son S, Nam J, Shin SW, Ochyl LJ, Meagher JL, Chang L, Stuckey JA, Song J, Montefiori DC, LaBranche CC, Smith JL, Xu J, Moon JJ§. Lipid-based vaccine nanoparticles for induction of humoral immune responses against HIV-1 and SARS-CoV-2. 330:529-539, 2021, Journal of Controlled Release. Link PDF


91. Kadiyala P, Carney SV, Gauss JC, Garcia-Fabiani MB, Haase S, Alghamri MS, Núñez FJ, Liu Y, Yu M, Taher AW, Nunez FM, Li D, Edwards MB, Kleer CG, Appelman H, Sun Y, Zhao L, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Inhibition of 2-Hydroxyglutarate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity in Mice. 131, 4, e139542, 2021, Journal of Clinical Investigation. Link PDF


2020

90. Chen XS, Moon JJ, Cheon J. New Opportunities in Cancer Immunotherapy and Theranostics. 53, 12:2763-2764, 2020, Accounts of Chemical Research. (Editorial) Link PDF


89. Aikins ME, Xu C, Moon JJ§. Engineered Nanoparticles for Cancer Vaccination and Immunotherapy. doi.org/10.1021/acs.accounts.0c00456, 2020, Accounts of Chemical Research. Link PDF


88. Zhou X, Jing X, Qu, M, Aninwene GE, Jacaud V, Moon JJ, Gu Z, Sun W, Khademhosseini A. Engineering Antiviral Vaccines. doi.org/10.1021/acsnano.0c06109, 2020, ACS Nano. Link PDF


87. Xu C, Hong H, Lee Y, Park KS, Sun M, Wang T, Aikins ME, Xu Y, Moon JJ§. Efficient Lymph Node-Targeted Delivery of Personalized Cancer Vaccines with Reactive Oxygen Species-Inducing Reduced Graphene Oxide Nanosheets. doi.org/10.1021/acsnano.0c05062, 2020, ACS Nano. Link PDF


86. Hassani Najafabadi A*, Zhang J*, Aikins ME, Najaf Abadi ZI, Liao F, Qin Y, Okeke EB, Scheetz LM, Nam J, Xu Y, Adams D, Lester P, Hetrick T, Schwendeman A, Wicha MS, Chang AE, Li Q§, Moon JJ§. Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs. doi.org/10.1021/acs.nanolett.0c03414, 2020, Nano Letters. Link PDF


85. Park KS, Xu C, Sun X, Louttit C, Moon JJ§. Improving STING Agonist Delivery for Cancer Immunotherapy Using Biodegradable Mesoporous Silica Nanoparticles. doi.org/10.1002/adtp.202000130, 2020, Advanced Therapeutics. Link PDF


84. Kuai R*, Singh PB*, Sun X*, Xu C, Najafabadi Hassani A, Scheetz L, Yuan W, Xu Y, Hong H, Keskin DB, Wu CJ, Jain R, Schwendeman A§, Moon JJ§. Robust Anti‐Tumor T Cell Response with Efficient Intratumoral Infiltration by Nanodisc Cancer Immunotherapy. doi: 10.1002/adtp.202000094, 2020, Advanced Therapeutics. Link PDF


83. Habibi N, Christau S, Ochyl LJ, Fan Z, Hassani Najafabadi A, Kuehnhammer M, Zhang M, Helgeson M, von Klitzing R, Moon JJ, Lahann J. Engineered Ovalbumin Nanoparticles for Cancer Immunotherapy. doi.org/10.1002/adtp.202000100, 2020, Advanced Therapeutics. Link PDF


82. Scheetz L*, Kadiyala P*, Sun X*, Son S, Najafabadi AH, Aikins, M, Lowenstein PR, Schwendeman A§, Castro MG§, Moon JJ§. Synthetic high-density lipoprotein nanodiscs for personalized immunotherapy against gliomas. doi: 10.1158/1078-0432.CCR-20-0341, 2020, Clinical Cancer Research. Link PDF


81. Scheetz L, Yu M, Li D, Castro MG, Moon JJ§, Schwendeman A§. Synthetic HDL Nanoparticles Delivering Docetaxel and CpG for Chemoimmunotherapy of Colon Adenocarcinoma. 21, 5, 1777, 2020, Int. J. Mol. Sci. Link PDF


80. Okeke EB, Louttit C, Fry C, Najafabadi AH, Han K, Nemzek J§, Moon JJ§. Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock. 238, 119836, 2020, Biomaterials. Link PDF


79. Son S*, Nam J*, Zenkov I, Ochyl LJ, Xu Y, Scheetz L, Shi J, Farokhzad OC§, Moon JJ§. Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination. doi: 10.1021/acs.nanolett.9b03483, 2020, Nano Letters. Link PDF


78. Garcia-Fabiani MB, Ventosa M, Comba A, Candolfi M, Nicola Candia AJ, Alghamri M, Kadiyala P, Carney S, Faisal SM, Schwendeman A, Moon JJ, Scheetz L, Lahann J, Mauser A, Lowenstein PR, Castro MG. Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development.  doi: 10.1080/13543784.2020.1768528, 2020, Expert Opin Investig Drugs. Link PDF


77. Draijer C, Speth JM, Penke LRK, Zaslona Z, Bazzill JD, Lugogo N, Huang YJ, Moon JJ, Peters-Golden M. Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation. doi: 10.1096/fj.201903089R, 2020, FASEB J. Link PDF


76. Altshuler DB, Kadiyala P, Nuñez FJ, Nuñez FM, Carney S, Alghamri MS, Garcia-Fabiani MB, Asad AS, Nicola Candia AJ, Candolfi M, Lahann J, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Prospects of biological and synthetic pharmacotherapies for glioblastoma. doi: 10.1080/14712598.2020.1713085, 2020, Expert Opin Biol Ther. Link PDF


2019

75. Xu C, Nam J, Hong H, Xu Y, Moon JJ. Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy. 13, 10, 12148-12161, 2019, ACS Nano. Link PDF


74. Bose RJ, Kim M, Chang JH, Paulmurugan R, Moon JJ, Koh WG, Lee SH, Park H. Biodegradable polymers for modern vaccine development. 77, 12-24, 2019, J. Industrial and Engineering Chemistry. Link PDF


73. Fan Y, Stronsky SM, Xu Y, Steffens JT, van Tongeren SA, Erwin A, Cooper CL*, Moon JJ*. Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection. 13, 10, 11087-11096, 2019, ACS Nano. Link PDF


72. Lee Y, Sugihara K, Gillilland MG 3rd, Jon S, Kamada N, Moon JJ. Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis. 19, 1, 118-126, 2020, Nature Materials. Link PDF

     * Featured by Nature Materials Link PDF & New England Journal of Medicine Link


71. Nam J*, Son S*, Park C, Zou W, Shea L, Moon JJ. Cancer nanomedicine for combination cancer immunotherapy. 4, 398-414, 2019, Nature Reviews Materials.  Link PDF


70. Scheetz L*, Park KS*, Li Q, Lowenstein PR, Castro MG, Schwendeman A, Moon JJ. Engineering strategies for personalized cancer immunotherapy: a paradigm shift. 3, 10, 768-782, 2019, Nature Biomedical Engineering. Link PDF


69. Louttit C*, Park KS*, Moon JJ. Bioinspired nucleic acid structures for immune modulation. 217, 119287, 2019, Biomaterials. Link PDF


68. Chen Z, Wholey WY, Hassani Najafabadi A, Moon JJ, Grigorova I, Chackerian B, Cheng W. Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help. 1801677, 2019, J Immunology. Link PDF


67. Speth JM, Penke LR, Bazzill JD, Park KS, de Rubio RG, Schneider DJ, Ouchi H, Moon JJ, Keshamouni VG, Zemans RL, Lama VN, Arenberg DA, Peters-Golden M. Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics. 4, 20, 131340, 2019, JCI Insight. Link PDF


66. Weerappuli PD*, Louttit C*, Kojima T, Brennan L*, Yalavarthi S, Xu Y, Ochyl JL, Maeda ML, Kim HS, Knight JS, Takayama S§, Moon JJ§. Extracellular trap-mimicking DNA-histone mesostructures synergistically activate dendritic cells. 8, 22, e1900926, 2019, Advanced Healthcare Materials. Link PDF


65. Lee Y, Arai Y, Ahn J, Kim D, Oh S, Kang D, Lee H, Moon JJ, Choi B, Lee SH. Three-dimensional microenvironmental priming of human mesenchymal stem cells in hydrogels facilitates efficient and rapid retroviral gene transduction via accelerated cell cycle synchronization. 11, 27, 2019, NPG Asia Materials. Link PDF


64. Wang T, Subramanian C, Yu M, White P, Kuai R, Sanchez J, Moon JJ, Timmermann BM, Schwendeman A, Cohen MS. Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer. 166, 6, 1168-1175, 2019, Surgery. Link PDF


63. Song Y, Kadiyala U, Weerappuli P, Valdez JJ, Yalavarthi S, Louttit C, Knight JS, Moon JJ, Weiss DS, VanEpps JS, and Takayama S. Antimicrobial Microwebs of DNA-Histone Inspired from Neutrophil Extracellular Traps. 31, 1807436, 2019, Advanced Materials.  Link PDF


62. Kadiyala P, Li D, Nuñez FM, Altshuler D, Doherty R, Kuai R, Yu M, Kamran N, Edwards M, Moon JJ, Lowenstein PR, Castro MG, and Schwendeman A. High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme. 13, 2, 1365-1384, 2019, ACS Nano.  Link PDF


61. Lee B, Ahn SY, Park C, Moon JJ, Lee JH, Luo D, Um SH, and Shin SW. Revealing the Presence of a Symbolic Sequence Representing Multiple Nucleotides Based on K-Means Clustering of Oligonucleotides. 24, 4, 348, 2019, Molecules.  Link PDF


2018

60. Bazzill JD, Ochyl LJ, Giang E, Castillo S, Law M*, and Moon JJ*. Interrogation of antigen display on individual vaccine nanoparticles for achieving neutralizing antibody responses against hepatitis C virus. doi: 10.1021/acs.nanolett.8b03601, 2018, Nano Letters. Link PDF

 

59. Ochyl LJ, and Moon JJ. Dendritic cell membrane vesicles for activation and maintenance of antigen‐specific T cells. http://doi.org/10.1002/adhm.201801091, 2018, Advanced Healthcare Materials. Link PDF

 

58. Bazzill JD*, Stronsky SM*, Kalinyak LC, Ochyl LJ, Steffens JT, van Tongeren SA, Cooper CL*, Moon JJ*. Vaccine nanoparticles displaying recombinant Ebola virus glycoprotein for induction of potent antibody and polyfunctional T cell responses. doi: 10.1016/j.nano.2018.11.005., 2018, Nanomedicine. Link PDF

 

57. Ochyl LJ, Bazzill JD, Park C, Xu Y, Kuai R, and Moon JJ. PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy. 182, 157-166, 2018, Biomaterials. Link PDF

 

56. Liu Z, Jiang W, Nam J, Moon JJ, and Kim BYS. Immunomodulating Nanomedicine for Cancer Therapy. 18, 11, 6655-6659, 2018, Nano Letters. Link PDF

 

55. Bose RJ, Kim BJ, Arai Y, Han IB, Moon JJ, Paulmurugan R, Park H, and Lee SH. Bioengineered stem cell membrane functionalized nanocarriers for therapeutic targeting of severe hindlimb ischemia. 185, 360-370, 2018, Biomaterials. Link  PDF

 

54. Moon JJ, Schwendeman SP, Schwendeman A. Nanomedicine: past, present, and future. 130, 1-2, 2018, Adv. Drug. Deliv. Rev. (Editorial) Link PDF

 

53. Mazzara JM, Ochyl LJ, Hong JKY, Moon JJ, Prausnitz MR, Schwendeman SP. Self-healing Encapsulation and Controlled Release of Vaccine Antigens from PLGA Microparticles and Microneedles. http://doi.org/10.1002/btm2.10103. 2018, Bioengineering & Translational Medicine. Link PDF

 

52. Subramanian C, White PT, Kuai R, Kalidindi A, Castle VP, Moon JJ, Timmermann BN, Schwendeman A, and Cohen MS. Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal, doi: 10.1016/j.surg.2018.01.023, 2018, Surgery. Link PDF

 

51. Kuai R, Sun X, Yuan W, Ochyl LJ, Xu Y, Hassani Najafabadi A, Scheetz L, Yu MZ, Balwani I, Schwendeman A*, and Moon JJ*. Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy. 282, 131-139, 2018, J Control Release. Link PDF

 

50. Moon JJ, Hennink WE, Schwendeman SP, Schwendeman A. NanoDDS 2017: The 15th International Nanomedicine & Drug Delivery Symposium. 282, 1-2, 2018, J Control Release (Editorial). Link PDF

 

49. Kuai R*, Yuan W*, Xu Y, Fan Y, Schwendeman A, Moon JJ. Elimination of established tumors with nanodisc-based combination chemoimmunotherapy. 4,4, eaao1736, 2018, Science Advances. Link PDF

 

48. Nam J*, Son S*, Ochyl LJ, Kuai R, Schwendeman A, and Moon JJ. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer. 9, 1, 1074, 2018, Nature Communications. Link PDF


47. Xu C, Chen F, Valdovinos HF, Jiang D, Goel S, Yu B, Sun H, Barnhart TE, Moon JJ, Cai W. Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. 165, 56-65, 2018, Biomaterials. Link PDF

 

46. Park HJ*, Kuai R*, Jeon EJ, Seo Y, Jung Y, Moon JJ, Schwendeman A, Cho SW. High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia. doi: 10.1016/j.biomaterials.2018.01.027, 2018, Biomaterials. Link PDF

 

45. Kuai R, Sun X, Yuan W, Xu Y, Schwendeman A, Moon JJ. Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy. 2018 doi: 10.1021/acs.bioconjchem.7b00761, 2018, Bioconjug Chem. Link PDF


44. Chen Z, Moon JJ, Cheng W. Quantitation and stability of protein conjugation on liposomes for controlled density of surface epitopes. doi: 10.1021/acs.bioconjchem.8b00033, 2018, Bioconjug Chem. Link PDF


43. Bose RJ, Paulmurugan R, Moon J, Lee SH, Park H. Cell membrane-coated nanocarriers: the emerging targeted delivery system for cancer theranostics. doi: 10.1016/j.drudis.2018.02.001, 2018, Drug Discov Today. Link PDF

 

42. Guo Y, Yuan W, Yu B, Kuai R, Hu W, Morin EE, Garcia-Barrio MT, Zhang J, Moon JJ, Schwendeman A, Eugene Chen Y. Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression. doi: 10.1016/j.ebiom.2017.12.021, 2018, EBioMedicine. Link PDF


2017

41. Fan Y, Kuai R, Xu Y, Ochyl LJ, Irvine DJ, and Moon JJ. Immunogenic cell death amplified by co-localized adjuvant delivery for cancer immunotherapy. 17(12):7387-739, 2017, Nano Letters. Link PDF

 

40. Kuai R, Subramanian C, White P, Moon JJ, Cohen MS, Schwendeman A. Synthetic high-density lipoproteins for targeted delivery of withalongolides to treat adrenocortical carcinoma, 12, 6581, 2017, Int. J. Nanomedicine. Link PDF

 

39. Nam J, Son S, Moon JJ. Adjuvant-loaded spiky gold nanoparticles for activation of innate immune cells, DOI: 10.1007/s12195-017-0505-8, 2017, Cellular and Molecular Bioengineering. Link PDF

 

38. Bailey BA, Desai KG, Ochyl LJ, Ciotti SM, Moon JJ, Schwendeman SP. Self-encapsulating poly(lactic-co-glycolic acid) (PLGA) microspheres for intranasal vaccine delivery, DOI: 10.1021/acs.molpharmaceut.7b00586, 2017, Molecular Pharmaceutics. Link PDF

 

37. Tang J, Kuai R, Yuan W, Drake L, Moon JJ, Schwendeman A. Effect of size and PEGylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting. 13, 1869-78, 2017, Nanomedicine. Link PDF

 

36. Kuai R, Ochyl LJ, Bahjat KS, Schwendeman A* and Moon JJ*. Designer vaccine nanodiscs for personalized cancer immunotherapy. 16, 4, 489-496, 2017, Nature Materials. Link PDF

** Featured by Nature World News, Science Alert, Fierce Biotech, Yahoo! News, R&D, eCancer, Medical Physics Web, Nanotechweb, Technology Networks, Technology.org, C2W.nl, La Stampa, Scientias, Controlled Environments, Tech Times, STRF.ru, Business Standard, CanIndia, La Razon, Health Canal, E! Informador, My Science, Azonano, Nanowerk, Health Medicine, The Medical News, Health Medicinet    Link

 

35. Bailey BA, Ochyl LJ, Schwendeman SP, and Moon JJ. Towards a single dose vaccination strategy with self-encapsulating PLGA microspheres. doi: 10.1002/adhm.201601418, 2017, Advanced Healthcare Materials. (most read article of the month) Link PDF

** Featured by Advanced Science News


34. Gao J, Ochyl LJ, Yang E, and Moon JJ. Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting degradation of antigens. 12, 1251-64, 2017, International J. Nanomedicine. Link PDF


33. Aikins M, Bazzill J, and Moon JJ. Vaccine nanoparticles for protection against HIV infection. 12, 6, 673-782, 2017, Nanomedicine (Lond). Link PDF


2016

32. Fan Y and Moon JJ. Particulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogens, doi:10.1002/wnan.1403. 2016, WIREs Nanomedicine & Nanobiotechnology(selected as the cover & one of the Top 10 most accessed articles in 2016) Link PDF

** Featured by Materials Views, Nanotechnology Now, Today Topics, and Phys.org


31. Kuai R, Li D, Chen YE, Moon JJ, and Schwendeman A. High density lipoproteins: nature’s multifunctional nanoparticles, 10, 3, 3015-41, 2016, ACS Nano. Link PDF


30. Subramanian C, Kuai R, Zhu Q, White P, Moon JJ, Schwendeman A, and Cohen MS. Synthetic high-density lipoprotein nanoparticles: a novel therapeutic strategy for adrenocortical carcinomas, 159, 1, 284-95, 2016, Surgery. Link PDF


29. Kuai R*, Ochyl LJ*, Schwendeman A, and Moon JJ. Lipid-based nanoparticles for vaccine applications. Book chapter in Biomedical Engineering: Frontier Research and Converging Technologies. Edited by Drs. Jo, Jun, Shin, and Lee, Springer, 9, 177-197, 2016.  (PEER-REVIEWED BOOK CHAPTER) Link


2015

28. Fan Y and Moon JJ. Nanoparticle vaccine delivery systems designed to improve cancer vaccines and immunotherapy, 3, 662-685, 2015, Vaccines. Link PDF


27. Fan Y*, Sahdev P*, Ochyl LJ, Akerberg J, and Moon JJ. Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens. 208, 121-9, 2015, J Control Release. Link PDF


26. Ochyl JL and Moon JJ. Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8+ T cell responses after nanoparticle vaccination, e52771, doi:10.3791/52771, 2015, JoVE. Link PDF


2014

25. Sahdev P, Ochyl JL, and Moon JJ. Biomaterials for nanoparticle vaccine delivery systems, 31, 2563-2582, 2014, Pharmaceutical Research. Link PDF


2013

24. Li AV*, Moon JJ*, Abraham W, Elkhader J, Suh K, Yen M, Im EJ, Barouch DH, and Irvine DJ. Generation of robust effector memory T-cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. 5, 204, 204ra130, 2013, Science Translational Medicine.  (selected as the cover) Link PDF

** Featured by Science News Daily, Chemistry Views, Newswise, Vaccine News, The Medical News, Medical News Today, Scicasts, MedicalXpress, LiveScience, Health Canal, and Nanowerk.

 

23. Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 MPER segments is dominated by residue accessibility and modulated by stereochemistry. 288, 44, 31888-901, 2013, J. Biol. Chem. Link PDF


2012

22. Demuth PC*, Moon JJ*, Suh H, Hammond PT, and Irvine DJ, and Huang B. Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery, 6, 8041-51, 2012, ACS Nano. Link PDF

 

21. Moon JJ, Huang B, and Irvine DJ. Engineering nano- and micro-particles to tune immunity, 24, 3724-462012, Advanced Materials. Link PDF


20. Moon JJ, Suh H, Li AV, Ockenhouse CF, Yadava A, and Irvine DJ. Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction, 109, 1080-52012, PNAS. Link PDF

   ** Featured by PNAS: Commentary, 109, 999-1000, 2012. Link PDF


19. Moon JJ, Suh H, Polhemus ME, Ockenhouse CF, Yadava A, and Irvine DJ. Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agent for Plasmodium vivax malaria vaccine, 7, e314722012, PLoS One. Link PDF

 

2011

18. Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu H, Huang B, Sohail M, Luo S, Um SH, Chiu W, and Irvine DJ. Interbilayer-crosslinked multilamellar vesicles for potent humoral and cellular immune responses, 10, 243-251, 2011, Nature Materials. Link PDF

** Featured by Nature Materials: News and Views, 10, 166-68, 2011, and Nature Biotech: Research Highlights, 29, 330, 2011. Link PDF

 

17. Bershteyn A, Hanson MC, Crespo MP, Moon JJ, Li AV, Suh H, and Irvine DJ. Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine, 157, 354-65, 2011, Journal of Controlled Release. Link PDF

 

2010

16. Stephan MT, Moon JJ, Um SH, Bershteyn A, and Irvine DJ. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles, 16, 1035-41, 2010, Nature Medicine. Link PDF

 

15. Moon JJ, Saik JE, Poche RA, Leslie-Barbick JE, Lee SH, Smith AA, Dickinson ME, and West JL. Biomimetic hydrogels with pro-angiogenic properties, 31, 3840-3847, 2010, Biomaterials. Link PDF

 

2009

14. Hu Y, Atukorale PU, Lu JJ, Moon JJ, Um SH, Cho EC, Wang Y, Chen J, and Irvine DJ. Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles, 10, 756-765, 2009, Biomacromolecules. Link PDF

 

13. Moon JJ, Hahn MS, Kim I, Nsiah BA, and West JL. Micropatterning of poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis, 15, 579-585, 2009, Tissue engineering - Part A. Link PDF

 

12. Leslie-Barbick JE, Moon JJ, and West JL. Covalently-Immobilized Vascular Endothelial Growth Factor Promotes Endothelial Cell Tubulogenesis in Poly(ethylene glycol) Diacrylate Hydrogels, 20, 1763-1779, 2009, Journal of biomaterials science – Polymer Edition Link PDF

 

2008

11. Moon JJ, and West JL. Vascularization of engineered tissues: approaches to promote angiogenesis in biomaterials, 8, 300-310, 2008, Current topics in medicinal chemistry. Link PDF

 

10. Lee SH*, Moon JJ*, and West JL. Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration, 29, 2962-2968, 2008, Biomaterials. * Authors contributed equally. Link PDF

 

9. Gobin AM*, Moon JJ*, and West JL. EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells, 3, 351-358, 2008, International journal of nanomedicine.  Link PDF

 

2007

8. Moon JJ, Lee SH, and West JL. Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis, 8, 42-49, 2007, Biomacromolecules. Link PDF

 

7. Lee SH, Moon JJ, Miller JS, and West JL. Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration, 28, 3163-3170, 2007, Biomaterials. Link PDF

 

2006

6. Hahn MS, Taite LJ, Moon JJ, Rowland MC, Ruffino KA, and West JL. Photolithographic patterning of polyethylene glycol hydrogels, 27, 2519-2524, 2006, Biomaterials. Link PDF

 

5. Lee P, Lin R, Moon J, and Lee LP. Microfluidic alignment of collagen fibers for in vitro cell culture, 8, 35-41, 2006, Biomedical microdevices. Link PDF

 

2005

4. DeLong SA, Moon JJ, and West JL. Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration, 26, 3227-3234, 2005, Biomaterials. Link PDF

 

3. Lee SH, Miller JS, Moon JJ, and West JL. Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration, 21, 1736-1741, 2005, Biotechnology Progress Link PDF

 

2. Moon JJ, Matsumoto M, Patel S, Lee L, Guan JL, and Li S. Role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction, 203, 166-176, 2005, J Cell Physiol. (selected as a cover) Link PDF

 

2003

1. Li S, Moon JJ, Miao H, Jin G, Chen BP, Yuan S, Hu Y, Usami S, and Chien S. Signal transduction in matrix contraction and the migration of vascular smooth muscle cells in three-dimensional matrix, 40, 378-388, 2003, J Vasc Res. Link PDF

a

MOON Laboratory


ImmunoEngineering