Faculty by Research Interest
(1) Metalloenzymes and Synthetic Metal Complexes
(2) De Novo Design of Proteins
(3) Detection and Regulation of Small/Large Molecules in Biology
(4) Metal Complexes in Medicine
(5) DNA, RNA, Reactive Nitrogen/Oxygen Species (RNOS), & Sulfur in Biology |
| (1) Metalloenzymes and Synthetic Metal Complexes |
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Dimitri Coucouvanis
Nitrogenase (Metal Cluster) |
Carol Fierke
Farnesyltransferase, Geranylgeranyl Transferase I, LpxC, & Histone Deacetylase 8 |
Katrin Karbstein
Fap7's ATPase, Endonuclease (Zinc-binding motif), & Iron-Sulfur Cluster/Proteins |
Nicolai Lehnert
Nitric Oxide Reductases, Metalloporphyrins, & Hydrogenase
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Mi Hee Lim
Nonheme Monooxygenases, Catalases, & Metalloporphyrins |
E. Neil G. Marsh
Glutamate Mutase, Benzylsuccinate Synthase, & Fluorous Proteins |
Rowena Matthews
Folate-Dependent Enzymes & Cobalamin-Dependent Enzymes |
Vincent Pecoraro
Manganese-Containing Enzymes: Catalase, Manganese Superoxide Dismutase, & the Oxygen Evolving Complex (Photosystem II, PSII)
Vanadium-Dependent Haloperoxidases |
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James Penner-Hahn
Zinc-Containing Enzymes for Alkyl Group Transfer
Determination of the Yeast Metallome |
A. Ramamoorthy
Membrane Proteins (Cytochrome b5, Cytochrome P450, High-Density Lipoprotein, & Myelin Basic Protein)
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Charles F. Yocum
Photosystem II, PSII
Managenase-Stabilizing Protein (Mn Ligation & Redox Cycling)
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(2) De Novo Design of Proteins |
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Carol Fierke
KDPG Aldolase |
Mi Hee Lim
Metallopeptides as Oxidation Catalysts
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E. Neil G. Marsh
Novel Proteins Incorporating Highly Fluorinated Amino Acids |
Vincent Pecoraro
Metallopeptides for Detexification of Heavy Metals |
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(3) Detection and Regulation of Small/Large Molecules in Biology |
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Kate Carroll
Chemical Probes for Sulfur Metabolism |
Carol Fierke
Biosensors:
Carbonic Anhydrase |
Katrin Karbstein
FRET Detection of the Fap7's ATPase Cycle |
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Robert Kennedy
Measurement of Neurotransmitters and Hormones both In Vivo and at Single Cells |
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Mi Hee Lim
Metal Ions in Human Brain Diseases |
Mark Meyerhoff
Copper-Based Nitric Oxide (NO)-Generating Polymers
Organodicalcogenide-Immobilized NOGPs |
Vincent Pecoraro
Metallopeptides for Detexification of Heavy Metals
Metallacrowns |
James Penner-Hahn
In Situ Imaging of Transition Metals in Biological Tissue |
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A. Ramamoorthy
Antimicrobial peptides (AMPs), Human AMPs, & Amyloid Peptides |
Nils Walter
Fluorescent Detection of the Enzymology of RNA, in bulk solution, in live cells, and at the single-molecule level |
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(4) Metal Complexes in Medicine |
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Dimitri Coucouvanis
Metal Complexes in Medicine & Cancer Treatement |
Mi Hee Lim
Transition Metal Complexes in Human Brain Diseases |
Vincent Pecoraro
Vanadium Complexes for Effective Diabetes
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(5) DNA, RNA, Reactive Nitrogen/Oxygen Species (RNOS), & Sulfur in Biology |
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Kate Carroll
Microbial Sulfur Metabolism & Cellular Redox Signaling |
Katrin Karbstein
Ribosome Assembly Complexes |
Nicolai Lehnert
Nitric Oxide in Biology |
Mi Hee Lim
Detoxification of Reactive Oxygen Species in Biology |
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Mark Meyerhoff
Nitric Oxide in Analytical Chemistry and Biology
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Nils Walter
Small RNA Catalysts (Hammerhead and Hepatitis Delta Virus Ribozymes in Human Gene Therapy and Relevance to Human Disease)
Large RNA-Protein Complexes (Ribosome, the Cellular Protein Synthesis Machinery)
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